Featured Publications
Heterogeneity of midgut cells and their differential responses to blood meal ingestion by the mosquito, Aedes aegypti
Cui Y, Franz AWE. Heterogeneity of midgut cells and their differential responses to blood meal ingestion by the mosquito, Aedes aegypti. Insect Biochemistry And Molecular Biology 2020, 127: 103496. PMID: 33188922, PMCID: PMC7739889, DOI: 10.1016/j.ibmb.2020.103496.Peer-Reviewed Original ResearchConceptsIntestinal stem cellsBlood meal ingestionMosquito midgutSingle-nucleus RNA sequencingCell type clustersCell typesVisceral muscle cellsNutrient absorptionCell type compositionHuman pathogenic parasitesNumerous mosquito speciesEC-like cellsBlood meal digestionEnteroendocrine cellsAedes aegyptiBlood-feeding behaviorMeal ingestionCellular homeostasisCellular diversityGenetic compatibilityHematophagous insectsFemale midgutTranscriptional profilesBlood digestionRNA sequencing
2022
Cellular diversity and gene expression profiles in the male and female brain of Aedes aegypti
Cui Y, Behura SK, Franz AWE. Cellular diversity and gene expression profiles in the male and female brain of Aedes aegypti. BMC Genomics 2022, 23: 119. PMID: 35144549, PMCID: PMC8832747, DOI: 10.1186/s12864-022-08327-9.Peer-Reviewed Original ResearchConceptsFemale brainMedulla neuronsCell clustersDimorphic behaviorsCell typesBrain cell typesSingle-nucleus RNA sequencingMonoaminergic neuronsProjection neuronsMosquito brainMale brainNeuronsKenyon cellsBrainYellow feverCell atlasCellular compositionGene expression profilesFemale mosquitoesGliaMosquito vectorsType compositionType proportionsRNA sequencingAdult males