2020
Quantification of myocardial blood flow (MBF) and reserve (MFR) incorporated with a novel segmentation approach: Assessments of quantitative precision and the lower limit of normal MBF and MFR in patients
Liu H, Thorn S, Wu J, Fazzone-Chettiar R, Sandoval V, Miller EJ, Sinusas AJ, Liu YH. Quantification of myocardial blood flow (MBF) and reserve (MFR) incorporated with a novel segmentation approach: Assessments of quantitative precision and the lower limit of normal MBF and MFR in patients. Journal Of Nuclear Cardiology 2020, 28: 1236-1248. PMID: 32715416, DOI: 10.1007/s12350-020-02278-y.Peer-Reviewed Original Research
2013
New Approach to Quantification of Molecularly Targeted Radiotracer Uptake from Hybrid Cardiac SPECT/CT: Methodology and Validation
Li S, Sinusas AJ, Dobrucki LW, Liu YH. New Approach to Quantification of Molecularly Targeted Radiotracer Uptake from Hybrid Cardiac SPECT/CT: Methodology and Validation. Journal Of Nuclear Medicine 2013, 54: 2175-2181. PMID: 24221992, DOI: 10.2967/jnumed.113.123208.Peer-Reviewed Original Research
2012
Left Ventricular Ejection Fraction and Left Ventricular End‐Diastolic Volume in Patients With Diastolic Dysfunction
Jovin IS, Ebisu K, Liu Y, Finta LA, Oprea AD, Brandt CA, Dziura J, Wackers FJ. Left Ventricular Ejection Fraction and Left Ventricular End‐Diastolic Volume in Patients With Diastolic Dysfunction. Congestive Heart Failure 2012, 19: 130-134. PMID: 23241105, DOI: 10.1111/chf.12013.Peer-Reviewed Original ResearchMeSH KeywordsDiastoleFemaleFollow-Up StudiesGated Blood-Pool ImagingHeartHumansMaleMiddle AgedReproducibility of ResultsRetrospective StudiesStroke VolumeVentricular Dysfunction, LeftConceptsLVEF of patientsLeft ventricular ejection fractionLower peak filling ratePeak filling rateEnd-diastolic volumeNormal peak filling ratesEquilibrium radionuclide angiocardiographyVentricular ejection fractionDiastolic dysfunctionAsymptomatic patientsEjection fractionLow left ventricular ejection fractionNormal left ventricular ejection fractionVentricular end-diastolic volumeMild systolic dysfunctionNormal systolic functionEDV indexSystolic dysfunctionSystolic functionRadionuclide angiocardiographyPatientsDysfunctionRepeat scansFilling rateAngiocardiography
2011
Accuracy and Reproducibility of Absolute Quantification of Myocardial Focal Tracer Uptake from Molecularly Targeted SPECT/CT: A Canine Validation
Liu YH, Sahul Z, Weyman CA, Dione DP, Dobrucki WL, Mekkaoui C, Brennan MP, Ryder WJ, Sinusas AJ. Accuracy and Reproducibility of Absolute Quantification of Myocardial Focal Tracer Uptake from Molecularly Targeted SPECT/CT: A Canine Validation. Journal Of Nuclear Medicine 2011, 52: 453-460. PMID: 21321271, PMCID: PMC3137905, DOI: 10.2967/jnumed.110.082214.Peer-Reviewed Original ResearchAnimalsDogsFemaleHeartImage Interpretation, Computer-AssistedMaleMetabolic Clearance RateMolecular ImagingMyocardial Perfusion ImagingMyocardiumRadiopharmaceuticalsReproducibility of ResultsSensitivity and SpecificitySubtraction TechniqueTissue DistributionTomography, Emission-Computed, Single-PhotonTomography, X-Ray Computed
2009
A novel three‐dimensional image reconstruction method for near‐field coded aperture single photon emission computerized tomography
Mu Z, Hong B, Li S, Liu Y. A novel three‐dimensional image reconstruction method for near‐field coded aperture single photon emission computerized tomography. Medical Physics 2009, 36: 1533-1542. PMID: 19544769, PMCID: PMC2832028, DOI: 10.1118/1.3103490.Peer-Reviewed Original Research
2006
Aperture Collimation Correction and Maximum-Likelihood Image Reconstruction for Near-Field Coded Aperture Imaging of Single Photon Emission Computerized Tomography
Mu Z, Liu YH. Aperture Collimation Correction and Maximum-Likelihood Image Reconstruction for Near-Field Coded Aperture Imaging of Single Photon Emission Computerized Tomography. IEEE Transactions On Medical Imaging 2006, 25: 701-711. PMID: 16768235, DOI: 10.1109/tmi.2006.873298.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsArtifactsData Interpretation, StatisticalFeasibility StudiesHumansImage EnhancementImage Interpretation, Computer-AssistedImaging, Three-DimensionalInformation Storage and RetrievalLikelihood FunctionsPhantoms, ImagingReproducibility of ResultsSensitivity and SpecificityTomography, Emission-Computed, Single-PhotonConceptsX-ray astronomySingle projectionCA imagesCoded Aperture ImagingMLEM reconstruction algorithmNear-field artifactsCollimation effectMaximum-likelihood image reconstructionSPECT systemParallel-hole collimatorImage reconstruction methodImage resolutionAperture imagingCollimationDeconvolution methodDual acquisitionImage reconstructionCount sensitivityImaging techniquesPhoton emissionPinholesReconstruction algorithm
2005
Clinical validation of SPECT attenuation correction using x-ray computed tomography–derived attenuation maps: Multicenter clinical trial with angiographic correlation
Masood Y, Liu Y, DePuey G, Taillefer R, Araujo LI, Allen S, Delbeke D, Anstett F, Peretz A, Zito M, Tsatkin V, Wackers FJ. Clinical validation of SPECT attenuation correction using x-ray computed tomography–derived attenuation maps: Multicenter clinical trial with angiographic correlation. Journal Of Nuclear Cardiology 2005, 12: 676-686. PMID: 16344230, DOI: 10.1016/j.nuclcard.2005.08.006.Peer-Reviewed Original ResearchNew hybrid count- and geometry-based method for quantification of left ventricular volumes and ejection fraction from ECG-gated SPECT: Methodology and validation
Liu YH, Sinusas AJ, Khaimov D, Gebuza BI, Wackers FJ. New hybrid count- and geometry-based method for quantification of left ventricular volumes and ejection fraction from ECG-gated SPECT: Methodology and validation. Journal Of Nuclear Cardiology 2005, 12: 55-65. PMID: 15682366, DOI: 10.1016/j.nuclcard.2004.09.015.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlgorithmsElectrocardiographyFemaleGated Blood-Pool ImagingHumansImage Interpretation, Computer-AssistedMaleMiddle AgedPhantoms, ImagingReproducibility of ResultsSensitivity and SpecificitySeverity of Illness IndexStroke VolumeTomography, Emission-Computed, Single-PhotonVentricular Dysfunction, LeftA New Method for SPECT Quantification of Targeted Radiotracers Uptake in the Myocardium
Li S, Dobrucki LW, Sinusas AJ, Liu YH. A New Method for SPECT Quantification of Targeted Radiotracers Uptake in the Myocardium. Lecture Notes In Computer Science 2005, 8: 684-691. PMID: 16686019, DOI: 10.1007/11566489_84.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDrug Delivery SystemsHeartImage Interpretation, Computer-AssistedMyocardiumNeovascularization, PathologicRadioisotopesRadiopharmaceuticalsRatsReperfusion InjuryReproducibility of ResultsSensitivity and SpecificityTomography, Emission-Computed, Single-PhotonVentricular Dysfunction, Left
1999
Quantification of regional myocardial wall thickening on electrocardiogram-gated SPECT imaging
Shen M, Liu Y, Sinusas A, Fetterman R, Bruni W, Drozhinin O, Zaret B, Wackers F. Quantification of regional myocardial wall thickening on electrocardiogram-gated SPECT imaging. Journal Of Nuclear Cardiology 1999, 6: 583-595. PMID: 10608585, DOI: 10.1016/s1071-3581(99)90095-8.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsComputer SimulationDiastoleElectrocardiographyHeart VentriclesHumansImage Processing, Computer-AssistedModels, CardiovascularMyocardial InfarctionObserver VariationPhantoms, ImagingPilot ProjectsRadiopharmaceuticalsReproducibility of ResultsSoftwareSystoleTechnetium Tc 99m SestamibiTomography, Emission-Computed, Single-PhotonVentricular Function, LeftVentricular RemodelingVentriculography, First-PassConceptsPrior myocardial infarctionRegional wall thickeningNormal subjectsMyocardial infarctionWall thickeningNormal wall thickeningPilot studyRegional left ventricular functionLeft ventricular functionAbnormal wall thickeningPercent count increaseECG-gated SPECT imagesSingle photon emissionSPECT imagesCardiac cycleLeft ventricular wallReproducibility of interpretationRegional left ventricular wallPrior infarctionCoronary diseaseVentricular functionValidation studyInfarct areaNormal rangeAnatomic areas