2022
Seizures and epilepsy in multiple sclerosis, aquaporin 4 antibody‐positive neuromyelitis optica spectrum disorder, and myelin oligodendrocyte glycoprotein antibody‐associated disease
Li E, Zheng Y, Cai M, Lai Q, Fang G, Du B, Shen C, Zhang Y, Wu L, Ding M. Seizures and epilepsy in multiple sclerosis, aquaporin 4 antibody‐positive neuromyelitis optica spectrum disorder, and myelin oligodendrocyte glycoprotein antibody‐associated disease. Epilepsia 2022, 63: 2173-2191. PMID: 35652436, DOI: 10.1111/epi.17315.Peer-Reviewed Original ResearchConceptsMyelin oligodendrocyte glycoprotein antibody-associated diseaseAquaporin-4 antibody-positive neuromyelitis optica spectrum disorderNeuromyelitis optica spectrum disorderAntibody-associated diseaseMultiple sclerosisCentral nervous system inflammatory demyelinating diseaseAutoimmune-associated epilepsyCerebral cortical encephalitisConcomitant systemic infectionPresence of status epilepticusAcute disseminated encephalomyelitisInflammatory demyelinating diseaseSecondary to inflammationAcute symptomatic seizuresDrug-drug interactionsAQP4-NMOSDCortical encephalitisMultiple relapsesDisseminated encephalomyelitisImpact of treatmentStatus epilepticusDisease activitySymptomatic seizuresAntiseizure medicationsInflammatory mechanisms
2020
Evaluation of brain and spinal cord lesion distribution criteria at disease onset in distinguishing NMOSD from MS and MOG antibody-associated disorder
Cai M, Zheng Y, Shen C, Yang F, Fang W, Zhang Y, Ding M. Evaluation of brain and spinal cord lesion distribution criteria at disease onset in distinguishing NMOSD from MS and MOG antibody-associated disorder. Multiple Sclerosis Journal 2020, 27: 871-882. PMID: 32672091, DOI: 10.1177/1352458520939008.Peer-Reviewed Original ResearchConceptsMyelin oligodendrocyte glycoprotein antibody-associated disorderNeuromyelitis optica spectrum disorderLongitudinally extensive transverse myelitisDifferentiate neuromyelitis optica spectrum disordersDisease onsetMultiple sclerosisAQP4-ab-seropositive neuromyelitis optica spectrum disorderLongitudinally extensive transverse myelitis lesionsDiagnostic performanceChinese populationAntibody-associated disordersAQP4-Ab seropositivityExtensive transverse myelitisEvaluation of brainVentricle lesionsTransverse myelitisRetrospective studyImaging criteriaPeriventricular lesionsAquaporin-4Finger lesionsLesionsDiseaseOnsetDisordersShort segment myelitis as the initial and only manifestation of aquaporin-4 immunoglobulin G-positive neuromyelitis optica spectrum disorders
Fang* W, Zheng* Y, Yang F, Cai M, Shen C, Liu Z, Zhang Y, Ding M. Short segment myelitis as the initial and only manifestation of aquaporin-4 immunoglobulin G-positive neuromyelitis optica spectrum disorders. Therapeutic Advances In Neurological Disorders 2020, 13: 1756286419898594. PMID: 32010226, PMCID: PMC6971969, DOI: 10.1177/1756286419898594.Peer-Reviewed Original ResearchNeuromyelitis optica spectrum disorderLongitudinally extensive transverse myelitisAquaporin-4 immunoglobulin G-positive neuromyelitis optica spectrum disorderManifestation of neuromyelitis optica spectrum disordersLongitudinally extensive transverse myelitis lesionsNMOSD diagnosisNeuromyelitis optica spectrum disorder patientsAquaporin-4 immunoglobulin GSpinal cord magnetic resonance imagingTwo-tailed Fisher's exact testExtensive transverse myelitisFisher's exact testMagnetic resonance imagingAQP4-IgGTransverse myelitisAcute myelitisRadiological featuresDelayed diagnosisChinese patientsAxial imagesCorrect diagnosisExact testStudy of lesionsSagittal imagesMyelitis