2022
Seizures and epilepsy in multiple sclerosis, aquaporin 4 antibody‐positive neuromyelitis optica spectrum disorder, and myelin oligodendrocyte glycoprotein antibody‐associated disease
Li E, Zheng Y, Cai M, Lai Q, Fang G, Du B, Shen C, Zhang Y, Wu L, Ding M. Seizures and epilepsy in multiple sclerosis, aquaporin 4 antibody‐positive neuromyelitis optica spectrum disorder, and myelin oligodendrocyte glycoprotein antibody‐associated disease. Epilepsia 2022, 63: 2173-2191. PMID: 35652436, DOI: 10.1111/epi.17315.Peer-Reviewed Original ResearchConceptsMyelin oligodendrocyte glycoprotein antibody-associated diseaseAquaporin-4 antibody-positive neuromyelitis optica spectrum disorderNeuromyelitis optica spectrum disorderAntibody-associated diseaseMultiple sclerosisCentral nervous system inflammatory demyelinating diseaseAutoimmune-associated epilepsyCerebral cortical encephalitisConcomitant systemic infectionPresence of status epilepticusAcute disseminated encephalomyelitisInflammatory demyelinating diseaseSecondary to inflammationAcute symptomatic seizuresDrug-drug interactionsAQP4-NMOSDCortical encephalitisMultiple relapsesDisseminated encephalomyelitisImpact of treatmentStatus epilepticusDisease activitySymptomatic seizuresAntiseizure medicationsInflammatory mechanisms
2020
IgG Index Revisited: Diagnostic Utility and Prognostic Value in Multiple Sclerosis
Zheng Y, Cai M, Yang F, Zhou J, Fang W, Shen C, Zhang Y, Ding M. IgG Index Revisited: Diagnostic Utility and Prognostic Value in Multiple Sclerosis. Frontiers In Immunology 2020, 11: 1799. PMID: 32973754, PMCID: PMC7468492, DOI: 10.3389/fimmu.2020.01799.Peer-Reviewed Original ResearchConceptsCohort of clinically isolated syndromeOligoclonal band positivityOligoclonal band statusOligoclonal bandsIgG indexPrognostic valueDiagnostic utilityMultiple sclerosisExpanded Disability Status Scale worseningAccurate diagnosis of multiple sclerosisMS diagnosisAttack of MSNegative oligoclonal bandsAsian populationsClinically isolated syndromeDiagnosis of multiple sclerosisElevated IgG indexEarly disease activityClinical relapseRetrospective studyDisease activityClinical challengeMS patientsAccurate diagnosisPredictive value