2024
Structural basis for transcription activation by the nitrate-responsive regulator NarL
Kompaniiets D, He L, Wang D, Zhou W, Yang Y, Hu Y, Liu B. Structural basis for transcription activation by the nitrate-responsive regulator NarL. Nucleic Acids Research 2024, 52: 1471-1482. PMID: 38197271, PMCID: PMC10853779, DOI: 10.1093/nar/gkad1231.Peer-Reviewed Original ResearchTranscription activation complexC-terminal domainTranscription activationAlpha C-terminal domainStructural basisGlobal transcription factorCryo-EM structureDetailed mechanistic understandingPromoter DNATranscription initiationBinds DNATranscription assaysTranscription factorsActivation complexÅ resolutionNarLDimer bindsMolecular mechanismsNovel mechanismActivation mechanismMechanistic understandingDNAStress factorsPromoterActivation
2023
Structure and molecular mechanism of bacterial transcription activation
Kompaniiets D, Wang D, Yang Y, Hu Y, Liu B. Structure and molecular mechanism of bacterial transcription activation. Trends In Microbiology 2023, 32: 379-397. PMID: 37903670, DOI: 10.1016/j.tim.2023.10.001.Peer-Reviewed Original ResearchTranscription activation mechanismTranscription activation complexTranscription activationGene expressionActivation mechanismRecent structural studiesSignal transduction processesTranscription activatorExtracellular signalsTAC componentsActivation complexMechanistic diversityMolecular mechanismsTransduction processesDifferent intracellularImportant checkpointStructural studiesStructural featuresActivationExpressionMechanismCheckpointDiversitySystematic classificationActivator