Photothermal‐Controllable Microneedles with Antitumor, Antioxidant, Angiogenic, and Chondrogenic Activities to Sequential Eliminate Tracheal Neoplasm and Reconstruct Tracheal Cartilage
Wang B, Fei X, Yin H, Xu X, Zhu J, Guo Z, Wu J, Zhu X, Zhang Y, Xu Y, Yang Y, Chen L. Photothermal‐Controllable Microneedles with Antitumor, Antioxidant, Angiogenic, and Chondrogenic Activities to Sequential Eliminate Tracheal Neoplasm and Reconstruct Tracheal Cartilage. Small 2023, 20: e2309454. PMID: 38098368, DOI: 10.1002/smll.202309454.Peer-Reviewed Original ResearchConceptsDecellularized cartilage matrixChondrogenic activityCartilage matrixIn situ polymerizationChondrogenic nicheCartilage regenerationChondrogenic effectCartilage reconstructionMethacrylic anhydrideNanosheetsManganese dioxideTumor excision siteInorganic nanosheetsPolydopamineCartilaginous matrixStem cell enrichmentHydrogelsMnOOrthotopic tumorsTracheal tumorsTumor eradicationTracheal neoplasmsMurine modelTumor elimination