Structural basis for transcription activation by the nitrate-responsive regulator NarL
Kompaniiets D, He L, Wang D, Zhou W, Yang Y, Hu Y, Liu B. Structural basis for transcription activation by the nitrate-responsive regulator NarL. Nucleic Acids Research 2024, 52: 1471-1482. PMID: 38197271, PMCID: PMC10853779, DOI: 10.1093/nar/gkad1231.Peer-Reviewed Original ResearchTranscription activation complexC-terminal domainTranscription activationAlpha C-terminal domainStructural basisGlobal transcription factorCryo-EM structureDetailed mechanistic understandingPromoter DNATranscription initiationBinds DNATranscription assaysTranscription factorsActivation complexÅ resolutionNarLDimer bindsMolecular mechanismsNovel mechanismActivation mechanismMechanistic understandingDNAStress factorsPromoterActivation