2014
Protein-protein Binding Detection with Nanoparticle Photonic Crystal Enhanced Microscopy (NP-PCEM)* *Research supported by National Science Foundation
Zhuo Y, Tian L, Chen W, Yu H, Singamaneni S, Cunningham B. Protein-protein Binding Detection with Nanoparticle Photonic Crystal Enhanced Microscopy (NP-PCEM)* *Research supported by National Science Foundation. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2014, 2014: 2069-2072. PMID: 25570391, DOI: 10.1109/embc.2014.6944023.Peer-Reviewed Original ResearchConceptsPhotonic crystalsLocalized surface plasmon resonance frequencyPC biosensorPhotonic crystal biosensorIndividual nanoparticlesSurface plasmon resonance frequencyPlasmon resonance frequencyResonance wavelengthExperimental demonstrationPresence of individual nanoparticlesBiosensing approachProtein-protein bindingBiosensorFunctionalized nanoparticlesNanoparticlesResonant frequencySurface adsorptionNanoparticle resolutionCrystalBinding detectionImaging approachResonanceFinite-differenceWavelength
2012
Visualization of Src and FAK Activity during the Differentiation Process from HMSCs to Osteoblasts
Liao X, Lu S, Zhuo Y, Winter C, Xu W, Wang Y. Visualization of Src and FAK Activity during the Differentiation Process from HMSCs to Osteoblasts. PLOS ONE 2012, 7: e42709. PMID: 22900044, PMCID: PMC3416797, DOI: 10.1371/journal.pone.0042709.Peer-Reviewed Original ResearchConceptsSrc activationFluorescence resonance energy transferFAK activationDifferentiation processActivation of FAKRegulates cellular adhesionSrc biosensorKinase FAKInduction of differentiationResonance energy transferFAKBiochemical signalsSrcCellular adhesionLiving cellsStem cellsOsteoblast differentiation processDifferentiationCellsBone cellsSrc/FAKInductionMesenchymal stem cellsActivityGenetics