2024
Mass Spectrometry Analysis of Nucleic Acid Modifications: From Beginning to Future
Xie Y, Brás‐Costa C, Lin Z, Garcia B. Mass Spectrometry Analysis of Nucleic Acid Modifications: From Beginning to Future. Mass Spectrometry Reviews 2024 PMID: 39308031, DOI: 10.1002/mas.21907.Peer-Reviewed Original ResearchMass spectrometryRegulate gene expressionMS-based methodsNucleic acidsNucleic acid structuresGenomic methodsTranscriptome researchModification statusGenetic informationNucleic acid modificationsProtein translationNucleic acid sample preparationBiological functionsGene expressionMS analysisSample preparationAcid structuresBiological moleculesModified speciesHigh-throughputDiverse modificationsLiving organismsAccurate quantitative informationAcid modificationGenome
2023
Analysis of Cell Glycogen with Quantitation and Determination of Branching Using Liquid Chromatography–Mass Spectrometry
Chen S, Bouchibti Y, Xie Y, Chen Y, Chang V, Lebrilla C. Analysis of Cell Glycogen with Quantitation and Determination of Branching Using Liquid Chromatography–Mass Spectrometry. Analytical Chemistry 2023, 95: 12884-12892. PMID: 37584460, DOI: 10.1021/acs.analchem.3c02230.Peer-Reviewed Original ResearchConceptsUHPLC/QqQ-MSDegree of branchingUltra-high-performance liquid chromatography/triple quadrupole mass spectrometryLiquid chromatography/triple quadrupole mass spectrometryQuadrupole mass spectrometryLiquid chromatography-mass spectrometryChromatography-mass spectrometryPMP derivatizationStructure determinationMass spectrometryDetermination of branchesHep G2) cellsLinkage analysisGlycogen phenotypeToxic to cellsBiological samplesHuman hepatocellular carcinomaBiological functionsSucrose gradientsEnzyme resultsGlucose residuesEffect of insulinSpectrometryInsulin-resistant statesFunction of glycogen