Heavy metals and metalloids exposure and liver function in Chinese adults — A nationally representative cross-sectional study
Wang S, Lyu Y, Ji S, Liu N, Wu B, Zhao F, Li Z, Qu Y, Zhu Y, Xie L, Li Y, Zhang Z, Song H, Hu X, Qiu Y, Zheng X, Zhang W, Yang Y, Li F, Cai J, Zhu Y, Cao Z, Tan F, Shi X. Heavy metals and metalloids exposure and liver function in Chinese adults — A nationally representative cross-sectional study. Environmental Research 2024, 252: 118653. PMID: 38518907, DOI: 10.1016/j.envres.2024.118653.Peer-Reviewed Original ResearchHeavy metalsEffects of heavy metalsChinese adultsHuman biomonitoring surveyMetalloid exposureBiomonitoring surveysEnvironmental presenceSample of Chinese adultsBenefits of seleniumCross-sectional studyHigher concentrationsNo significant associationMetalloidsLiver functionAspartate aminotransferaseAlcohol consumptionAlanine aminotransferaseAlcohol intakeSeleniumManganeseSignificant associationHealthMetalLiver healthAnalyzed dataMediating Role of Liver Dysfunction in the Association between Arsenic Exposure and Diabetes in Chinese Adults: A Nationwide Cross-Sectional Study of China National Human Biomonitoring (CNHBM) 2017–2018
Ji S, Qu Y, Sun Q, Zhao F, Qiu Y, Li Z, Li Y, Song H, Zhang M, Zhang W, Fu H, Cai J, Zhang Z, Zhu Y, Cao Z, Lv Y, Shi X. Mediating Role of Liver Dysfunction in the Association between Arsenic Exposure and Diabetes in Chinese Adults: A Nationwide Cross-Sectional Study of China National Human Biomonitoring (CNHBM) 2017–2018. Environmental Science And Technology 2024, 58: 2693-2703. PMID: 38285630, DOI: 10.1021/acs.est.3c08718.Peer-Reviewed Original ResearchConceptsSerum alanine aminotransferaseLiver dysfunctionAlanine aminotransferaseNationwide cross-sectional studyRestricted cubic spline modelsGeneralized linear mixed modelsEffects of liver dysfunctionMediation analysisCross-sectional studyArsenic exposureAspartate aminotransferaseCubic spline modelsHuman biomonitoringAssociated with TADiabetes prevalenceChinese adultsLow-to-moderateLinear mixed modelsUrinary totalLowest quartileAlcohol consumptionLiver diseaseOverall populationDiabetes