2024
Active Surveillance or Watchful Waiting for Intermediate-Risk Prostate Cancer, 2010-2020
Ajjawi I, Loeb S, Cooperberg M, Catalona W, Gross C, Ma X, Leapman M. Active Surveillance or Watchful Waiting for Intermediate-Risk Prostate Cancer, 2010-2020. JAMA 2024, 332 PMID: 39565605, PMCID: PMC11579888, DOI: 10.1001/jama.2024.20580.Peer-Reviewed Original ResearchPD45-10 PROSTATE-SPECIFIC MEMBRANE ANTIGEN IMAGING FINDINGS AND SUBSEQUENT CLINICAL MANAGEMENT AMONG PATIENTS WITH BIOCHEMICAL RECURRENT PROSTATE CANCER: A RETROSPECTIVE COHORT STUDY
Leapman M, Rabil M, Ghaffar U, Long J, Westvold S, Sprenkle P, Kim I, Saperstein L, Fallah J, Suzman D, Lerro C, Xu J, Kluetz P, Kunst N, Wang S, Ma X, Gross C, Karnes R. PD45-10 PROSTATE-SPECIFIC MEMBRANE ANTIGEN IMAGING FINDINGS AND SUBSEQUENT CLINICAL MANAGEMENT AMONG PATIENTS WITH BIOCHEMICAL RECURRENT PROSTATE CANCER: A RETROSPECTIVE COHORT STUDY. Journal Of Urology 2024, 211: e971. DOI: 10.1097/01.ju.0001008792.09108.b4.10.Peer-Reviewed Original Research
2023
PD10-01 ASSOCIATIONS BETWEEN PROSTATE MRI AND GENOMIC TESTING AND TREATMENT INTENSIFICATION AMONG PATIENTS WITH LOCALIZED PROSTATE CANCER
Leapman M, Wang R, Long J, Sprenkle P, Ma X, Gross C. PD10-01 ASSOCIATIONS BETWEEN PROSTATE MRI AND GENOMIC TESTING AND TREATMENT INTENSIFICATION AMONG PATIENTS WITH LOCALIZED PROSTATE CANCER. Journal Of Urology 2023, 209: e326. DOI: 10.1097/ju.0000000000003250.01.Peer-Reviewed Original Research“It just makes sense to me”: Patient experiences with prostate MRI during prostate cancer active surveillance.
Sutherland R, Gross C, Ma X, Jeong F, Seibert T, Cooperberg M, Catalona W, Loeb S, Schulman-Green D, Leapman M. “It just makes sense to me”: Patient experiences with prostate MRI during prostate cancer active surveillance. Journal Of Clinical Oncology 2023, 41: 334-334. DOI: 10.1200/jco.2023.41.6_suppl.334.Peer-Reviewed Original ResearchActive surveillanceProstate cancerProstate MRIPatient experienceGleason Grade Group 1Prostate cancer active surveillanceIntermediate-risk prostate cancerRisk prostate cancerGrade group 1Group 2 tumorsMRI-ultrasound fusion biopsyMean sample ageHispanics/LatinosInitial diagnosisFusion biopsyProstate biopsyConventional content analysisPatient's perspectiveClinical careGroup 1MRI resultsMRI scansProviders' explanationsCancerPatientsOutdoor artificial light at night, air pollution, and risk of childhood acute lymphoblastic leukemia in the California Linkage Study of Early-Onset Cancers
Zhong C, Wang R, Morimoto L, Longcore T, Franklin M, Rogne T, Metayer C, Wiemels J, Ma X. Outdoor artificial light at night, air pollution, and risk of childhood acute lymphoblastic leukemia in the California Linkage Study of Early-Onset Cancers. Scientific Reports 2023, 13: 583. PMID: 36631468, PMCID: PMC9834257, DOI: 10.1038/s41598-022-23682-z.Peer-Reviewed Original ResearchConceptsAcute lymphoblastic leukemiaRisk of childhoodEarly-onset cancersLymphoblastic leukemiaBirth recordsChildhood acute lymphoblastic leukemiaNon-Hispanic white childrenHispanic childrenCalifornia Cancer RegistryEtiology of childhoodOutdoor artificial lightOutdoor ALANHighest tertileCancer RegistryLinkage studiesRisk factorsBorderline associationElevated riskCancer diagnosisCancerEnvironmental exposuresWhite childrenCommon typeAir pollutionRisk
2022
International patterns and trends of childhood and adolescent cancer, 1978-2012
Zhao Y, Sun P, Xiao J, Jin L, Ma N, Li Z, Feng G, Huang H, Deziel N, Ma X, Ni X, Zhang Y. International patterns and trends of childhood and adolescent cancer, 1978-2012. Journal Of The National Cancer Center 2022, 2: 78-89. PMID: 39034956, PMCID: PMC11256536, DOI: 10.1016/j.jncc.2022.02.001.Peer-Reviewed Original ResearchCancer incidence ratesIncidence rateCancer incidenceMalignant central nervous system tumorsCentral nervous system tumorsOverall childhood cancerIncidence of lymphomaNervous system tumorsLeukemia incidence ratesSystem tumorsTesticular cancerChildhood cancerThyroid cancerAdolescent cancerKidney cancerJoinpoint regressionCancer incidentsAge groupsCancerCancer typesIncidenceTemporal trendsMethods DataAdolescentsChildren
2021
Mediators of racial disparity in the use of prostate MRI.
Leapman M, Dinan M, Pasha S, Washington S, Ma X, Gross C. Mediators of racial disparity in the use of prostate MRI. Journal Of Clinical Oncology 2021, 39: 6554-6554. DOI: 10.1200/jco.2021.39.15_suppl.6554.Peer-Reviewed Original ResearchProstate cancerRacial disparitiesProstate MRIMRI useArea-level measuresObserved racial disparitiesEligible patientsPathologic factorsDual eligibilityWhite patientsBlack patientsSEER regionMedicare databaseCancer careSix-month periodPatientsSociodemographic factorsCancerMRIZip codesOlder AmericansMediatorsDiagnostic toolObserved disparitiesHigh-poverty areasA Stakeholder-Driven Qualitative Study to Define High Quality End-of-Life Care for Children With Cancer
Ananth P, Mun S, Reffat N, Li R, Sedghi T, Avery M, Snaman J, Gross CP, Ma X, Wolfe J. A Stakeholder-Driven Qualitative Study to Define High Quality End-of-Life Care for Children With Cancer. Journal Of Pain And Symptom Management 2021, 62: 492-502. PMID: 33556497, PMCID: PMC8339188, DOI: 10.1016/j.jpainsymman.2021.01.134.Peer-Reviewed Original ResearchConceptsHigh-quality endQuality EOLCAdvanced cancerSymptom managementLife careQuality endLocation of deathMulticenter qualitative studyAvoidance of hospitalizationPerson-centered measuresCancer stakeholdersEnd of lifeSupportive careMechanical ventilationParents of childrenEmergency departmentInterdisciplinary careInterdisciplinary healthcare professionalsCardiopulmonary resuscitationHospice careQualitative studyCancerHealthcare professionalsFamily preferencesYoung adults
2020
MP23-17 ASSOCIATIONS OF REGIONAL-LEVEL ADOPTION OF PROSTATE MRI AND GENOMIC TESTING AND OBSERVATION FOR PROSTATE CANCER
Leapman* M, Wang R, Ma X, Gross C. MP23-17 ASSOCIATIONS OF REGIONAL-LEVEL ADOPTION OF PROSTATE MRI AND GENOMIC TESTING AND OBSERVATION FOR PROSTATE CANCER. Journal Of Urology 2020, 203 DOI: 10.1097/ju.0000000000000856.017.Peer-Reviewed Original ResearchSpatial-Temporal Cluster Analysis of Childhood Cancer in California.
Francis SS, Enders C, Hyde R, Gao X, Wang R, Ma X, Wiemels JL, Selvin S, Metayer C. Spatial-Temporal Cluster Analysis of Childhood Cancer in California. Epidemiology 2020, 31: 214-223. PMID: 31596791, PMCID: PMC9005107, DOI: 10.1097/ede.0000000000001121.Peer-Reviewed Original ResearchConceptsMalignant gonadal germ cell tumorsGonadal germ cell tumorsGerm cell tumorsAcute lymphoblastic leukemiaChildhood cancerCell tumorsChildhood acute lymphoblastic leukemiaYears of ageRace/ethnicity-matched controlsEthnicity-matched controlsSpace-time cluster analysisEpidemiologic featuresHodgkin's lymphomaLymphoblastic leukemiaBirth addressHealth professionalsCancerSpace-time clustersTumorsAgeSaTScanTemporal cluster analysisFurther researchEvidenceLymphoma
2019
Immunoepidemiology of Cancer
Ma X, Wang R. Immunoepidemiology of Cancer. 2019, 215-224. DOI: 10.1007/978-3-030-25553-4_13.Peer-Reviewed Original ResearchImmune system functionTypes of cancerImmunological factorsCancer immunotherapyTreatment modalitiesChronic diseasesRadiation therapyEpidemiological studiesDrug AdministrationImmunotherapyInfectious diseasesCancerDiseaseExciting new eraSystem functionChemotherapySurgeryImmunoepidemiologyEtiologyTherapyYearsInfectionAdministrationImportant role
2018
Association Between Prostate Magnetic Resonance Imaging and Observation for Low-risk Prostate Cancer
Leapman MS, Wang R, Park HS, Yu JB, Weinreb JC, Gross CP, Ma X. Association Between Prostate Magnetic Resonance Imaging and Observation for Low-risk Prostate Cancer. Urology 2018, 124: 98-106. PMID: 30107188, DOI: 10.1016/j.urology.2018.07.041.Peer-Reviewed Original ResearchConceptsLow-risk prostate cancerProstate magnetic resonance imagingMagnetic resonance imagingProstate cancerDefinitive treatmentPCa diagnosisEnd Results-Medicare databaseResonance imagingMultivariable logistic regression analysisPropensity scoreDiagnosis of PCaUse of MRIConditional logistic regression modelsLogistic regression analysisLogistic regression modelsInitial managementMultivariable analysisGreater oddsPatientsSocioeconomic statusDiagnosisHigher likelihoodRegression analysisDemographic factorsCancerPhysician peer group characteristics and timeliness of breast cancer surgery
Bachand J, Soulos PR, Herrin J, Pollack CE, Xu X, Ma X, Gross CP. Physician peer group characteristics and timeliness of breast cancer surgery. Breast Cancer Research And Treatment 2018, 170: 657-665. PMID: 29693229, PMCID: PMC6048589, DOI: 10.1007/s10549-018-4789-8.Peer-Reviewed Original ResearchConceptsPhysician peer groupsSurgical delayProvider densityPatient racial compositionBreast cancerEnd Results-Medicare dataBreast cancer patientsBreast cancer surgeryResultsThe study sampleConclusionsThe likelihoodBlack patientsCancer surgeryCancer patientsSurgeryPatientsStudy sampleWomenCancerAssociationGroupGroup characteristicsPurposeLittleInterdisciplinary groupPeer groupEpidemiologyMP53-08 USE OF PROSTATE MAGNETIC RESONANCE IMAGING AMONG MEDICARE BENEFICIARIES WITH LOW-RISK PROSTATE CANCER IS ASSOCIATED WITH A HIGHER LIKELIHOOD OF DEFINITIVE TREATMENT
Leapman M, Wang R, Park H, Yu J, Gross C, Ma X. MP53-08 USE OF PROSTATE MAGNETIC RESONANCE IMAGING AMONG MEDICARE BENEFICIARIES WITH LOW-RISK PROSTATE CANCER IS ASSOCIATED WITH A HIGHER LIKELIHOOD OF DEFINITIVE TREATMENT. Journal Of Urology 2018, 199: e707. DOI: 10.1016/j.juro.2018.02.1679.Peer-Reviewed Original Research
2017
Regional Medicare Expenditures and Survival Among Older Women With Localized Breast Cancer
Tannenbaum S, Soulos PR, Herrin J, Mougalian S, Long JB, Wang R, Ma X, Gross CP, Xu X. Regional Medicare Expenditures and Survival Among Older Women With Localized Breast Cancer. Medical Care 2017, 55: 1030-1038. PMID: 29068906, PMCID: PMC5863278, DOI: 10.1097/mlr.0000000000000822.Peer-Reviewed Original ResearchConceptsBreast cancer careHospital referral regionsNonmetastatic breast cancerBreast cancerCancer careMedicare beneficiariesMedicare expendituresCancer expendituresBetter survivalEnd Results-MedicareRetrospective cohort studyPatients 3 yearsClinical characteristicsCohort studyOverall survivalCancer stagePatient outcomesOutcome measuresReferral regionsOlder womenSignificant associationStage IIBivariate analysisCancerQuintile
2015
Organophosphate insecticide use and cancer incidence among spouses of pesticide applicators in the Agricultural Health Study
Lerro CC, Koutros S, Andreotti G, Friesen MC, Alavanja MC, Blair A, Hoppin JA, Sandler DP, Lubin JH, Ma X, Zhang Y, Freeman L. Organophosphate insecticide use and cancer incidence among spouses of pesticide applicators in the Agricultural Health Study. Occupational And Environmental Medicine 2015, 72: 736. PMID: 26150671, PMCID: PMC4909328, DOI: 10.1136/oemed-2014-102798.Peer-Reviewed Original ResearchConceptsCancer incidenceRelative riskCancer riskPesticide applicatorsAgricultural Health Study cohortOP useHealth Study cohortAgricultural Health StudyNon-Hodgkin lymphomaReproductive health historyStudy cohortPotential confoundersOvarian cancerThyroid cancerBreast cancerElevated riskEpidemiological studiesHealth StudyHealth historyPoisson regressionMale populationCancerFurther evaluationDemographic informationSpecific organophosphatesThe Role of Patient Factors, Cancer Characteristics, and Treatment Patterns in the Cost of Care for Medicare Beneficiaries with Breast Cancer
Xu X, Herrin J, Soulos PR, Saraf A, Roberts KB, Killelea BK, Wang SY, Long JB, Wang R, Ma X, Gross CP. The Role of Patient Factors, Cancer Characteristics, and Treatment Patterns in the Cost of Care for Medicare Beneficiaries with Breast Cancer. Health Services Research 2015, 51: 167-186. PMID: 26119176, PMCID: PMC4722219, DOI: 10.1111/1475-6773.12328.Peer-Reviewed Original ResearchConceptsBreast cancer careHospital referral regionsCancer careMedicare expendituresBreast cancerRadiation therapyTreatment factorsMean Medicare expendituresEnd Results-MedicareSpecific treatment modalitiesContribution of patientCost of careHighest spending quintilePatient factorsTreatment patternsTumor characteristicsCancer characteristicsTreatment modalitiesReferral regionsMedicare beneficiariesQuintilePatientsCancerCareTherapyOlder Women With Localized Breast Cancer: Costs And Survival Rates Increased Across Two Time Periods
Feinstein AJ, Long J, Soulos PR, Ma X, Herrin J, Frick KD, Chagpar AB, Krumholz HM, Yu JB, Ross JS, Gross CP. Older Women With Localized Breast Cancer: Costs And Survival Rates Increased Across Two Time Periods. Health Affairs 2015, 34: 592-600. PMID: 25847641, DOI: 10.1377/hlthaff.2014.1119.Peer-Reviewed Original ResearchConceptsStage II diseaseStage III diseaseCancer-related costsCancer careBreast cancerMedian costSurvival rateEnd Results Program-MedicareFive-year survivalCancer care costsBreast surgerySurvival outcomesImproved outcomesOlder womenRadiation therapyCare costsStage IIDiseaseStudy periodWomenCancerCareSignificant national attentionOutcomesPercentUse of acetochlor and cancer incidence in the Agricultural Health Study
Lerro CC, Koutros S, Andreotti G, Hines CJ, Blair A, Lubin J, Ma X, Zhang Y, Beane Freeman L. Use of acetochlor and cancer incidence in the Agricultural Health Study. International Journal Of Cancer 2015, 137: 1167-1175. PMID: 25559664, PMCID: PMC4492894, DOI: 10.1002/ijc.29416.Peer-Reviewed Original ResearchConceptsAgricultural Health StudyLung cancerPancreatic cancerCancer incidenceRelative riskHealth StudyColorectal cancer riskExposure-response trendsAdditional potential confoundersRisk of melanomaTime of interviewIncident cancerColorectal cancerPotential confoundersEpidemiologic studiesCancer riskPoisson regressionCancerTelephone interviewsPesticide applicatorsDefinitive conclusionsConfidence intervalsRiskMelanomaIncidence
2013
The cost implications of prostate cancer screening in the Medicare population
Ma X, Wang R, Long JB, Ross JS, Soulos PR, Yu JB, Makarov DV, Gold HT, Gross CP. The cost implications of prostate cancer screening in the Medicare population. Cancer 2013, 120: 96-102. PMID: 24122801, PMCID: PMC3867600, DOI: 10.1002/cncr.28373.Peer-Reviewed Original ResearchConceptsProstate cancerScreening costsAnnual screening costsPopulation-based cohortProstate cancer screeningHospital referral region levelMale Medicare beneficiariesProstate-specific antigenCancer screeningLowest quartileHRR levelMedicare populationMedicare beneficiariesOlder menNational feeCancerService Medicare programCancer diagnosisMenQuartilePSACost implicationsAnnual expenditureMedicare programBiopsy