2023
Health disparities in preterm births
Brown J, Chang X, Matson A, Lainwala S, Chen M, Cong X, Casavant S. Health disparities in preterm births. Frontiers In Public Health 2023, 11: 1275776. PMID: 38162611, PMCID: PMC10757361, DOI: 10.3389/fpubh.2023.1275776.Peer-Reviewed Original ResearchConceptsPreterm birth rateNeonatal intensive care unitPreterm infantsPreterm birthNon-Hispanic white (WNeonatal Infant Stressor ScaleBirth rateClinical treatment informationHealth disparitiesImprove social determinants of healthIntensive care unitSocial determinants of healthOutcome inequalityDeterminants of healthImprove social determinantsElectronic health recordsNeurodevelopmental outcomesPretermHospital stayAdverse health outcomesAnthropometric measurementsLifesaving procedureLife course approachCross-sectional analysisCare unit
2022
Associations of Mitochondrial Function, Stress, and Neurodevelopmental Outcomes in Early Life: A Systematic Review
Zhao T, Alder N, Starkweather A, Chen M, Matson A, Xu W, Balsbaugh J, Cong X. Associations of Mitochondrial Function, Stress, and Neurodevelopmental Outcomes in Early Life: A Systematic Review. Developmental Neuroscience 2022, 44: 438-454. PMID: 35995037, PMCID: PMC9928905, DOI: 10.1159/000526491.Peer-Reviewed Original ResearchConceptsNeurodevelopmental outcomesPreterm infantsEarly life stressPostnatal stressSystematic reviewInfluence neurodevelopmental outcomesMitochondrial function/dysfunctionEarly lifeAssociated with stress exposurePreferred Reporting ItemsFull-termPrimary research articlesBIOSIS databasesInfluence of biological sexLife stressLack of longitudinal dataInfant stressInfantsReporting ItemsPretermInvasive samplingOutcomesStress exposureBehavioral changesFunction/dysfunctionEarly-life factors associated with neurobehavioral outcomes in preterm infants during NICU hospitalization
Zhao T, Griffith T, Zhang Y, Li H, Hussain N, Lester B, Cong X. Early-life factors associated with neurobehavioral outcomes in preterm infants during NICU hospitalization. Pediatric Research 2022, 92: 1695-1704. PMID: 35338349, PMCID: PMC9509490, DOI: 10.1038/s41390-022-02021-y.Peer-Reviewed Original ResearchConceptsNeonatal Infant Stressor ScalePreterm infantsNeurobehavioral outcomesBreastmilk intakeGestational ageNICU hospitalizationMaternal breastmilkAssociated with increasing GADay of NICU hospitalizationWeeks post-menstrual ageNICU Network Neurobehavioral ScalePoorer quality of movementOlder gestational agePost-menstrual ageMethodsA prospective cohort studyNISS scoresInfant neurobehavioral outcomesProspective cohort studyDays of lifeConclusionsPreterm infantsGA infantsYounger GAPain/stressNeurobehavioral ScalePreterm
2021
Multivariate log‐contrast regression with sub‐compositional predictors: Testing the association between preterm infants' gut microbiome and neurobehavioral outcomes
Liu X, Cong X, Li G, Maas K, Chen K. Multivariate log‐contrast regression with sub‐compositional predictors: Testing the association between preterm infants' gut microbiome and neurobehavioral outcomes. Statistics In Medicine 2021, 41: 580-594. PMID: 34897772, DOI: 10.1002/sim.9273.Peer-Reviewed Original ResearchConceptsLinear log-contrast modelLog-contrast modelGut microbiomeGut microbiome of preterm infantsHypothesis testing procedureInfant gut microbiomeLinear constraintsCompositional covariatesInference proceduresMultivariate responsePenalization approachSimulation studyGroup structureMicrobiome dataIdentified microbesMicrobiome analysisTaxonomic hierarchyInference methodsPreterm infant studyTest procedureMicrobiomeMicrobesBiological understandingCovariatesFeature matrixSex Differences in Gut Microbial Development of Preterm Infant Twins in Early Life: A Longitudinal Analysis
Chen J, Li H, Hird S, Chen M, Xu W, Maas K, Cong X. Sex Differences in Gut Microbial Development of Preterm Infant Twins in Early Life: A Longitudinal Analysis. Frontiers In Cellular And Infection Microbiology 2021, 11: 671074. PMID: 34458157, PMCID: PMC8387566, DOI: 10.3389/fcimb.2021.671074.Peer-Reviewed Original ResearchConceptsStatistical Analysis of Metagenomic ProfilesNeonatal intensive care unitGut microbiotaGut microbiomeFunction of gut microbiotaCharacteristics of gut microbiotaReconstruction of Unobserved StatesPhylogenetic Investigation of CommunitiesGut microbial developmentGut microbiota patternInfant gut microbiotaGut microbiota compositionGut microbiome diversityInvestigation of CommunitiesInfant gut microbiomePostnatal ageNeurobehavioral developmentMetagenomic functionsMixed-sex groupsPhylogenetic investigationMetagenomic profilesEnvironmental factorsMicrobiota compositionKEGG pathwaysMicrobiome diversityMulti-Omics Analysis on Neurodevelopment in Preterm Neonates
Casavant S, Chen J, Xu W, Lainwala S, Matson A, Chen M, Starkweather A, Maas K, Cong X. Multi-Omics Analysis on Neurodevelopment in Preterm Neonates. Nursing Research 2021, 70: 462-468. PMID: 34380978, PMCID: PMC8563389, DOI: 10.1097/nnr.0000000000000548.Peer-Reviewed Original ResearchConceptsPreterm infantsIntensive care unitNecrotizing enterocolitisFeeding intoleranceNeurodevelopmental impairmentNeonatal intensive care unit periodAdverse outcomesHost genetic variationIntestinal microbiomePreterm infants born <Care unitNeonatal intensive care unitInfants born <Weeks gestational ageGut microbiomeIntensive care unit periodFollow-up visitRegulation of intestinal healthPreterm neonatesGestational agePotential adverse outcomesNeurodevelopmental outcomesPain sensitivityPretermMulti-omics analysis
2019
Feeding modes, duration, and diarrhea in infancy: Continued evidence of the protective effects of breastfeeding
Diallo A, McGlothen‐Bell K, Lucas R, Walsh S, Allen C, Henderson W, Cong X, McGrath J. Feeding modes, duration, and diarrhea in infancy: Continued evidence of the protective effects of breastfeeding. Public Health Nursing 2019, 37: 155-160. PMID: 31709650, DOI: 10.1111/phn.12683.Peer-Reviewed Original ResearchConceptsAssociated with higher oddsHigher oddsIncidence of diarrheaMother-infant dyadsInfant Feeding Practices Study IIPublic health interventionsEarly breastfeeding cessationProtective effectSecondary data analysisDiverse population groupsHealth interventionsCommunity settingsBreastfeeding interruptionBreastfeeding practicesBreastfeeding cessationBreastfeeding objectivesExclusive breastfeedingFormula feedingU.S. infantsDiarrheaStudy IIBreastfeedingPopulation groupsMonthsOddsAllostatic Load and Biomarkers of Stress in the Preterm Infant: An Integrative Review
Casavant S, Cong X, Fitch R, Moore J, Rosenkrantz T, Starkweather A. Allostatic Load and Biomarkers of Stress in the Preterm Infant: An Integrative Review. Biological Research For Nursing 2019, 21: 210-223. PMID: 30654634, DOI: 10.1177/1099800418824415.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unitPreterm infantsLong-term outcome measuresMarkers of oxidative stressIntensive care unitBorn pretermNociceptive inputNonnoxious stimuliBrain-gut-microbiome axisPretermPainful proceduresCare unitHuman studiesInclusion criteriaLife-saving careTherapeutic interventionsInfantsOutcome measuresEarly detectionTime pointsBiomarkersActivation of stress responsesCortisol levelsOxidative stressSystematic search
2018
Factors Affecting Breastfeeding Outcomes at Six Months in Preterm Infants
Wang Y, Briere C, Xu W, Cong X. Factors Affecting Breastfeeding Outcomes at Six Months in Preterm Infants. Journal Of Human Lactation 2018, 35: 80-89. PMID: 29723482, DOI: 10.1177/0890334418771307.Peer-Reviewed Original ResearchConceptsPreterm infantsPrevalence of breastfeedingLevel of breastfeeding self-efficacyMothers of very preterm infantsFactors associated with exclusive breastfeedingPreterm mother-infant dyadsIntensive careBreastfeeding practicesLate preterm infantsVery preterm infantsInfant gestational ageMonths corrected ageNeonatal intensive careYoung maternal ageElevated EPDS scoresPerception of breastfeeding self-efficacyImprove breastfeeding durationGestational agePostpartum depressive symptomsCorrected ageLongitudinal observational studyPreterm mothersDepressive symptomsPretermMaternal age
2017
Increase in Oxytocin From Skin-to-Skin Contact Enhances Development of Parent–Infant Relationship
Vittner D, McGrath J, Robinson J, Lawhon G, Cusson R, Eisenfeld L, Walsh S, Young E, Cong X. Increase in Oxytocin From Skin-to-Skin Contact Enhances Development of Parent–Infant Relationship. Biological Research For Nursing 2017, 20: 54-62. PMID: 29017336, DOI: 10.1177/1099800417735633.Peer-Reviewed Original ResearchConceptsSkin-to-skin contactNeonatal intensive care unitStable preterm infantsOT levelsSkin-to-skinParent-infant contactIntensive care unitRandomized crossover studySC levelsPreterm infantsHigher OT levelsCrossover studyOT releaseParental OTParental anxiety scoresDay 1Care unitSalivary cortisolPre-SSCInfant stressInfantsPost-SSCParent-infant interactionOxytocinSaliva samples
2016
Management of childhood diarrhea by healthcare professionals in low income countries: An integrative review
Diallo A, Cong X, Henderson W, McGrath J. Management of childhood diarrhea by healthcare professionals in low income countries: An integrative review. International Journal Of Nursing Studies 2016, 66: 82-92. PMID: 28043020, DOI: 10.1016/j.ijnurstu.2016.08.014.Peer-Reviewed Original ResearchConceptsManagement of childhood diarrhoeaHealthcare professionalsLow-income countriesChildhood diarrheaBehaviour of healthcare professionalsReporting of Observational StudiesInfluence prescription behavioursHealthcare professionals' managementObservational studyCombination of research designsOral rehydration solutionCross sectional studyYear of study publicationHealthcare providersPrimary caregiversIntegrative reviewAdequate careWorld Health OrganizationChild mortalityCase-controlRehydration solutionIncome countriesHealthcareSectional studyAdequate knowledge
2015
Direct-Breastfeeding Premature Infants in the Neonatal Intensive Care Unit
Briere C, McGrath J, Cong X, Brownell E, Cusson R. Direct-Breastfeeding Premature Infants in the Neonatal Intensive Care Unit. Journal Of Human Lactation 2015, 31: 386-392. PMID: 25900843, DOI: 10.1177/0890334415581798.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unitDirect breastfeedingOral feedingBreastfeeding goalsInfants born <Weeks gestational ageRetrospective chart reviewPrenatal care providersIntensive care unitHuman milkGestational agePremature deliveryPremature infantsChart reviewLogistic regression modelsCare unitShorter lengthHigh riskInfantsBreastfeedingNon-HispanicChi-squareBreastMothersCare providers
2006
Breast and Infant Temperatures With Twins During Shared Kangaroo Care
Ludington‐Hoe S, Lewis T, Morgan K, Cong X, Anderson L, Reese S. Breast and Infant Temperatures With Twins During Shared Kangaroo Care. Journal Of Obstetric Gynecologic & Neonatal Nursing 2006, 35: 223-231. PMID: 16620248, PMCID: PMC1890034, DOI: 10.1111/j.1552-6909.2006.00024.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultBody TemperatureBreastClinical Nursing ResearchDiseases in TwinsFemaleHumansHypothermiaInfantInfant CareInfant, NewbornInfant, PrematureInfant, Premature, DiseasesIntensive Care, NeonatalMonitoring, PhysiologicNeonatal NursingNursing AssessmentNursing Evaluation ResearchPosturePregnancyTime FactorsTwins
2002
Infant Crying: Nature, Physiologic Consequences, and Select Interventions
Ludington-Hoe S, Cong X, Hashemi F. Infant Crying: Nature, Physiologic Consequences, and Select Interventions. Neonatal Network The Journal Of Neonatal Nursing 2002, 21: 29-36. PMID: 11923998, DOI: 10.1891/0730-0832.21.2.29.Peer-Reviewed Original ResearchConceptsNursing interventionsBlood pressureInfant cryingMother-infant interactionSelective interventionsInterventionKangaroo careLong-term sequelaeBrain injuryRhythmic movementsMother's voiceHeart rateNursesCaregiversCareIncreased heart rateValsalva maneuverHeartbeat soundsMothersPacifierCardiac dysfunctionCrying