2024
Multi-Omics Analysis of Gut Microbiota and Host Transcriptomics Reveal Dysregulated Immune Response and Metabolism in Young Adults with Irritable Bowel Syndrome
Chen J, Zhao T, Li H, Xu W, Maas K, Singh V, Chen M, Dorsey S, Starkweather A, Cong X. Multi-Omics Analysis of Gut Microbiota and Host Transcriptomics Reveal Dysregulated Immune Response and Metabolism in Young Adults with Irritable Bowel Syndrome. International Journal Of Molecular Sciences 2024, 25: 3514. PMID: 38542485, PMCID: PMC10970623, DOI: 10.3390/ijms25063514.Peer-Reviewed Original ResearchConceptsGut microbiotaIrritable bowel syndrome subjectsHost transcriptomeIrritable bowel syndromeMetabolic pathways of gut microbiotaTranscriptome profilingAnalysis of gut microbiotaDysbiosis of gut microbiotaDysregulated immune responseRNA-seq dataHealthy controlsMulti-omics analysisImmune responseImmune system processRNA-seqGene OntologyBowel syndromeIBS participantsMulti-omicsMicrobiotaMetabolic pathwaysPathways of antigen processingPeripheral blood samplesGutStool samples
2023
“They're scared that somebody's gonna judge them”: Female African American youth in Foster Care's perspectives on sexual and reproductive health communication with caregivers
Ross C, Smith J, Gawel M, Walters T, Song Y, Cong X, Shook N. “They're scared that somebody's gonna judge them”: Female African American youth in Foster Care's perspectives on sexual and reproductive health communication with caregivers. Journal Of Pediatric Nursing 2023, 75: 8-15. PMID: 38091927, DOI: 10.1016/j.pedn.2023.11.024.Peer-Reviewed Original ResearchConceptsSexual and reproductive healthSexual and reproductive health informationHealthcare providersCare perspectiveSRH communicationYouths' sexual and reproductive healthSexual and reproductive health communicationAccurate SRH informationSexual and reproductive health topicsSexual and reproductive health knowledgeFemale African American adolescentsAdverse childhood experiencesReproductive health communicationSemi-structured interviewsTrauma-informed approachBiological parentsCare dependencyTranscribed interviewsClinical encountersCommunication interventionsCaregiversQualitative studySRH informationHealth communicationPurposive sampling
2022
Somatosensory Profiles Differentiate Pain and Psychophysiological Symptoms Among Young Adults With Irritable Bowel Syndrome
Chen J, Zhang Y, Barandouzi Z, Xu W, Feng B, Chon K, Santos M, Starkweather A, Cong X. Somatosensory Profiles Differentiate Pain and Psychophysiological Symptoms Among Young Adults With Irritable Bowel Syndrome. The Clinical Journal Of Pain 2022, 38: 492-501. PMID: 35686579, PMCID: PMC9205184, DOI: 10.1097/ajp.0000000000001046.Peer-Reviewed Original ResearchMeSH KeywordsCluster AnalysisHumansIrritable Bowel SyndromeNociceptive PainPain MeasurementPain ThresholdYoung AdultConceptsIrritable bowel syndromeIrritable bowel syndrome patientsHealthy controlsPain intensityPain thresholdBowel syndromeIBS-related painSomatic pain perceptionQuantitative sensory testingIncreased pain thresholdYoung adultsRandomized clinical trialsSelf-management interventionsSomatosensory profilesDifferentiate painPain perceptionPsychophysiological symptomsFollow-upClinical trialsPainNormal thresholdsIncreased thresholdSensory thresholdsSevere symptomsPatientsThe effect of self-management online modules plus nurse-led support on pain and quality of life among young adults with irritable bowel syndrome: A randomized controlled trial
Chen J, Zhang Y, Barandouzi Z, Lee J, Zhao T, Xu W, Chen M, Feng B, Starkweather A, Cong X. The effect of self-management online modules plus nurse-led support on pain and quality of life among young adults with irritable bowel syndrome: A randomized controlled trial. International Journal Of Nursing Studies 2022, 132: 104278. PMID: 35640500, PMCID: PMC10588769, DOI: 10.1016/j.ijnurstu.2022.104278.Peer-Reviewed Original ResearchMeSH KeywordsChronic PainHumansIrritable Bowel SyndromeNurse's RoleQuality of LifeSelf-ManagementYoung AdultConceptsQuality of lifeImprove quality of lifeNurse-led interventionNurse-ledIntervention groupIntervention effectsPain interferenceOnline modulesImprove qualitySelf-managementNurse-led self-management programIrritable bowel syndromeYoung adultsSelf-efficacyNurse-led supportEffects of self-managementLife-long self-managementSelf-management programReducing pain interferenceSelf-reported painFollow-upIncreased quality of lifeBaseline data collectionIncreased self-efficacyDecreased pain intensityAssociations of neurotransmitters and the gut microbiome with emotional distress in mixed type of irritable bowel syndrome
Barandouzi Z, Lee J, del Carmen Rosas M, Chen J, Henderson W, Starkweather A, Cong X. Associations of neurotransmitters and the gut microbiome with emotional distress in mixed type of irritable bowel syndrome. Scientific Reports 2022, 12: 1648. PMID: 35102266, PMCID: PMC8803858, DOI: 10.1038/s41598-022-05756-0.Peer-Reviewed Original ResearchConceptsEmotional distressNeurotransmitter levelsHealthy controlsIrritable bowel syndrome groupIrritable bowel syndromeRegulation of neurotransmittersDepressive symptomsSerotonin levelsGut-brain axisEmotional symptomsHC groupPlasma neurotransmittersDistressGut microbiome profilesNeurotransmitterGut microbiomeNorepinephrine levelsBowel syndromeMicrobiome profilesPersonsNorepinephrineNested case-control studySymptomsCase-control studySerotoninPsychosocial and Sensory Factors Contribute to Self-Reported Pain and Quality of Life in Young Adults with Irritable Bowel Syndrome
Chen J, Barandouzi Z, Lee J, Xu W, Feng B, Starkweather A, Cong X. Psychosocial and Sensory Factors Contribute to Self-Reported Pain and Quality of Life in Young Adults with Irritable Bowel Syndrome. Pain Management Nursing 2022, 23: 646-654. PMID: 35074280, PMCID: PMC9300766, DOI: 10.1016/j.pmn.2021.12.004.Peer-Reviewed Original ResearchConceptsSelf-reported painQuality of lifePressure pain thresholdBrief Pain InventoryPsychosocial factorsSelf-efficacyPain interferenceIBS-QOLIrritable bowel syndromeAssociated with pain interferenceCross-sectional analysis of baseline dataPain thresholdAnalysis of baseline dataYoung adultsImprove pain managementMediation analysisCross-sectional analysisSensory factorsRandomized controlled trialsPain InventoryPain managementIntervention studiesAlcohol intakeCold pain thresholdGeneral community
2016
A survey of skin-to-skin contact with perinatal nurses
Vittner D, Cong X, Ludington-Hoe S, McGrath J. A survey of skin-to-skin contact with perinatal nurses. Applied Nursing Research 2016, 33: 19-23. PMID: 28096017, DOI: 10.1016/j.apnr.2016.09.006.Peer-Reviewed Original ResearchConceptsImplementation of SSCNurses' responsesPerinatal nursesEducation levelPractice settingsYears of nursing practicePrimary practice settingKnowledge-practice gapCross-sectional survey designSkin-to-skin contactYears of practiceNurses' knowledgeNursing practiceOrdered logistic regressionSSC implementationNursesNurse objectsDescriptive statisticsLogistic regressionSurvey designYears experienceInfluence attitudesEducationPracticeAge differences
2012
Maternal consumption of a DHA-containing functional food benefits infant sleep patterning: An early neurodevelopmental measure
Judge M, Cong X, Harel O, Courville A, Lammi-Keefe C. Maternal consumption of a DHA-containing functional food benefits infant sleep patterning: An early neurodevelopmental measure. Early Human Development 2012, 88: 531-537. PMID: 22269042, DOI: 10.1016/j.earlhumdev.2011.12.016.Peer-Reviewed Original ResearchConceptsInfant sleep patternsPlacebo groupSleep organizationInfant sleep/wake stateMaternal DHA intakeFetal neural tissuePlacebo-controlled designPostnatal day 1Early neurobehavioral developmentSleep patternsPlacebo barWeeks gestationPostnatal hoursDouble-blindPregnancy complicationsQuiet sleepActive sleepMaternal consumptionDHA intakeSleep/wake statesDay 1Neurobehavioral developmentPrenatal supplyPregnancyOrganism sleep
2011
Kangaroo Care and Behavioral and Physiologic Pain Responses in Very-Low-Birth-Weight Twins: A Case Study
Cong X, Cusson R, Hussain N, Zhang D, Kelly S. Kangaroo Care and Behavioral and Physiologic Pain Responses in Very-Low-Birth-Weight Twins: A Case Study. Pain Management Nursing 2011, 13: 127-138. PMID: 22929600, DOI: 10.1016/j.pmn.2010.10.035.Peer-Reviewed Original ResearchConceptsPreterm Infant Pain ProfilePhysiological pain responsesHeel stickPain responseKangaroo careInfant BVery-low-birth-weightPainful proceduresGestational age twinsIncidence of apneaLF/HF ratioSympathetic-parasympathetic balanceHeart rate variability indicesPreterm infantsIncubator careLow-frequency powerPain ProfilePain scoresHigh-frequency powerCrying timeBradycardia episodesBaseline levelsInfantsPretermIC conditions