2024
Multi-Omics Analysis of Gut Microbiota and Host Transcriptomics Reveal Dysregulated Immune Response and Metabolism in Young Adults with Irritable Bowel Syndrome
Chen J, Zhao T, Li H, Xu W, Maas K, Singh V, Chen M, Dorsey S, Starkweather A, Cong X. Multi-Omics Analysis of Gut Microbiota and Host Transcriptomics Reveal Dysregulated Immune Response and Metabolism in Young Adults with Irritable Bowel Syndrome. International Journal Of Molecular Sciences 2024, 25: 3514. PMID: 38542485, PMCID: PMC10970623, DOI: 10.3390/ijms25063514.Peer-Reviewed Original ResearchConceptsGut microbiotaIrritable bowel syndrome subjectsHost transcriptomeIrritable bowel syndromeMetabolic pathways of gut microbiotaTranscriptome profilingAnalysis of gut microbiotaDysbiosis of gut microbiotaDysregulated immune responseRNA-seq dataHealthy controlsMulti-omics analysisImmune responseImmune system processRNA-seqGene OntologyBowel syndromeIBS participantsMulti-omicsMicrobiotaMetabolic pathwaysPathways of antigen processingPeripheral blood samplesGutStool samples
2020
Altered Composition of Gut Microbiota in Depression: A Systematic Review
Barandouzi Z, Starkweather A, Henderson W, Gyamfi A, Cong X. Altered Composition of Gut Microbiota in Depression: A Systematic Review. Frontiers In Psychiatry 2020, 11: 541. PMID: 32587537, PMCID: PMC7299157, DOI: 10.3389/fpsyt.2020.00541.Peer-Reviewed Original ResearchGut microbiota patternMicrobiota patternsComposition of gut microbiotaLow abundanceClostridium IV</i>Clostridium XlVa</i>Gut microbiome patternsBrain-gut-microbiome axisGenus levelGut microbiotaB-diversityGut microbiomePhylum levelA-diversityMicrobiome patternsGastrointestinal microbiomeFamily levelMicrobiome findingsMicrobiotaAltered compositionAbundanceGutHealthy controlsMicrobiomeDepressive disorder