Role of myeloid-derived suppressor cells in type 1 diabetes (167.16)
Yen C, Chen S, Pan P, Pan C, Yang W. Role of myeloid-derived suppressor cells in type 1 diabetes (167.16). The Journal Of Immunology 2011, 186: 167.16-167.16. DOI: 10.4049/jimmunol.186.supp.167.16.Peer-Reviewed Original ResearchMyeloid-derived suppressor cellsType 1 diabetesSuppressor cellsNOD/SCID miceT cellsMechanisms of action of MDSCsPresence of myeloid-derived suppressor cellsAutoimmune diseasesAutoimmune destruction of pancreatic isletsInduction of peripheral toleranceSuppression of T cell proliferationCD4+CD25+Foxp3+ TregsT cell suppressionDiabetic NOD miceInflammatory T cellsSingle-dose treatmentT cell proliferationAbstract Type 1 diabetesSuppress immune responsesDestruction of pancreatic isletsAnti-inflammation cytokinesSuppressed T1DAdoptive transferEffective immunotherapyPeripheral tolerance