2022
Expression and Potential Prognostic Value of SOX9, MCL-1 and SPOCK1 in Gastric Adenocarcinoma
Luo W, Nagaria T, Sun H, Ma J, Lombardo J, Bassett R, Cao A, Tan D. Expression and Potential Prognostic Value of SOX9, MCL-1 and SPOCK1 in Gastric Adenocarcinoma. Pathology & Oncology Research 2022, 28: 1610293. PMID: 35221802, PMCID: PMC8863590, DOI: 10.3389/pore.2022.1610293.Peer-Reviewed Original ResearchConceptsGastric cancerPrognostic valueGastric adenocarcinomaMcl-1Pathologic TNM stageDifferent treatment modalitiesCancer-related deathPotential prognostic valueFurther subgroup analysisNegative prognostic markerTumor heterogeneityDifferent molecular alterationsSOX9 expressionSPOCK1 expressionPrognostic roleCommon malignancyPoor prognosisTNM stageTreatment modalitiesSubgroup analysisPrognostic markerUnivariate analysisDisease prognosisDivergent differentiationMolecular alterations
2018
CDH1 Gene and Hereditary Diffuse Gastric Cancer Syndrome: Molecular and Histological Alterations and Implications for Diagnosis And Treatment
Luo W, Fedda F, Lynch P, Tan D. CDH1 Gene and Hereditary Diffuse Gastric Cancer Syndrome: Molecular and Histological Alterations and Implications for Diagnosis And Treatment. Frontiers In Pharmacology 2018, 9: 1421. PMID: 30568591, PMCID: PMC6290068, DOI: 10.3389/fphar.2018.01421.Peer-Reviewed Original ResearchInternational Gastric Cancer Linkage ConsortiumHereditary diffuse gastric cancer syndromeGastric cancer syndromeGastric cancerMutation carriersGermline mutationsCancer syndromesCommon germline mutationsProphylactic total gastrectomyInvasive lobular carcinomaOptimal surveillance strategySporadic diffuse gastric cancerRecent histologic studiesFamilial gastric cancerDiffuse gastric cancerMost cancer mortalityTotal gastrectomySurgical candidatesDismal prognosisCommon malignancyHistological findingsLobular carcinomaCancer mortalityColorectal cancerColorectal adenocarcinoma