2022
Differences in white matter segments in autistic males, non-autistic siblings, and non-autistic participants: An intermediate phenotype approach
Chien YL, Chen YJ, Tseng WL, Hsu YC, Wu CS, Tseng WI, Gau SS. Differences in white matter segments in autistic males, non-autistic siblings, and non-autistic participants: An intermediate phenotype approach. Autism 2022, 27: 1036-1052. PMID: 36254873, DOI: 10.1177/13623613221125620.Peer-Reviewed Original ResearchConceptsNon-autistic siblingsNon-autistic peopleAutistic peopleAutistic traitsBrain regionsTheory of mindNon-autistic participantsHigher cognitive functionsAnterior brain regionsSocial cognitionNeurocognitive strengthsNeuropsychological characteristicsCognitive functionAutistic malesDifferent brain regionsAutismBrain adaptationIntermediate phenotype approachWhite matter differencesFuture researchNeural pathwaysBiological basisPeopleSiblingsCausal link
2020
Executive functions in youths with autism spectrum disorder and their unaffected siblings
Seng GJ, Tseng WL, Chiu YN, Tsai WC, Wu YY, Gau SS. Executive functions in youths with autism spectrum disorder and their unaffected siblings. Psychological Medicine 2020, 51: 2571-2580. PMID: 32349803, DOI: 10.1017/s0033291720001075.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSpatial working memoryExecutive function tasksExecutive functionASD youthWorking memoryFunction tasksCognitive endophenotypesSpatial spanExecutive dysfunctionSpectrum disorderUnaffected siblingsCambridge Neuropsychological Test Automated BatteryAttention-deficit/hyperactivity disorderPotential cognitive endophenotypesExtra-dimensional shiftPlanning/problemVisuospatial working memoryBackward digit recallMain cognitive theoriesStockings of CambridgeDigit span testEvidence of deficitsCognitive theoryDigit recall