2023
Evaluation of Birth Weight and Neurodevelopmental Conditions Among Monozygotic and Dizygotic Twins
Isaksson J, Ruchkin V, Ljungström T, Bölte S. Evaluation of Birth Weight and Neurodevelopmental Conditions Among Monozygotic and Dizygotic Twins. JAMA Network Open 2023, 6: e2321165. PMID: 37389871, PMCID: PMC10314302, DOI: 10.1001/jamanetworkopen.2023.21165.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderLow birth weightBirth weightHigh birth weightLower oddsNeurodevelopmental conditionsIntellectual disabilityFetal growth restrictionCase-control studyMonozygotic twinsDizygotic twinsTwin pairsMedian ageGrowth restrictionMAIN OUTCOMEGenetic predispositionEarly identificationCo-twin studyMonozygotic pairsDiagnostic assessmentHyperactivity disorderParticipant visitsGenetic riskADHD diagnosisDizygotic pairs
2022
Nonshared environmental factors in the aetiology of autism and other neurodevelopmental conditions: a monozygotic co-twin control study
Isaksson J, Ruchkin V, Aho N, Lundin Remnélius K, Marschik P, Bölte S. Nonshared environmental factors in the aetiology of autism and other neurodevelopmental conditions: a monozygotic co-twin control study. Molecular Autism 2022, 13: 8. PMID: 35183250, PMCID: PMC8858556, DOI: 10.1186/s13229-022-00487-5.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderAutism spectrum disorderNeurodevelopmental conditionsCo-twin designHyperactivity disorderSpectrum disorderCo-twin control studyEarly environmental riskLower IQAutismEtiology of autismIntellectual disabilityPrevious researchEarly interventionEarly childhoodConclusionsThe findingsPostnatal riskEquation modelMonozygotic co‐twin control studyBackgroundA significant proportionRisk loadSeparate risk factorsTwin pairsTargeted preventionWeight discordance