Variation in the catechol-O-methyltransferase Val158Met polymorphism associated with conduct disorder and ADHD symptoms, among adolescent male delinquents
DeYoung CG, Getchell M, Koposov RA, Yrigollen CM, Haeffel GJ, Klinteberg B, Oreland L, Ruchkin VV, Pakstis AJ, Grigorenko EL. Variation in the catechol-O-methyltransferase Val158Met polymorphism associated with conduct disorder and ADHD symptoms, among adolescent male delinquents. Psychiatric Genetics 2010, 20: 20-24. PMID: 19997043, PMCID: PMC2895253, DOI: 10.1097/ypg.0b013e32833511e4.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderCatechol-O-methyltransferase (COMT) geneConduct disorderADHD symptomsHigh-risk populationCatechol-O-methyltransferase (COMT) Val158Met polymorphismCOMT geneDeficit/hyperactivity disorderConduct disorder diagnosisBehavior problemsSymptomsVal alleleMet alleleDisorder diagnosisHyperactivity disorderVal158Met polymorphismDisordersAntisocial behavior