Vishwa Deep Dixit, DVM, PhD

Son of teachers, Deep grew up in Hisar (Northwest India). He studied Veterinary Medicine in India, did PhD Research in University of Hannover Germany and postdoc research in Morehouse School of Medicine and NIH. He currently holds Waldemar Von Zedtwitz endowed chair and is a Professor in the Departments of Pathology, Comparative Medicine and Immunobiology and is the director of Yale Center for Research on Aging. Dixit lab studies Immunometabolism and aging. His team help establish NLRP3 inflammasome in causing ‘inflammaging’ and immunosenescence that leads to age-related chronic diseases including metabolic dysfunction. Dixit and his collaborators have identified that switch from glycolysis to ketogenesis deactivates the inflammasome and reduces immunopathology. The ongoing work in his laboratory is aimed at understanding how adaptation to negative energy balance in a host can be harnessed to identify immunometabolic checkpoints to enhance health and lifespan.