1998
Galanin–5-hydroxytryptamine interactions: electrophysiological, immunohistochemical and in situ hybridization studies on rat dorsal raphe neurons with a note on galanin R1 and R2 receptors
Xu Z, Zhang X, Pieribone VA, Grillner S, Hökfelt T. Galanin–5-hydroxytryptamine interactions: electrophysiological, immunohistochemical and in situ hybridization studies on rat dorsal raphe neurons with a note on galanin R1 and R2 receptors. Neuroscience 1998, 87: 79-94. PMID: 9722143, DOI: 10.1016/s0306-4522(98)00151-1.Peer-Reviewed Original ResearchConceptsDorsal raphe neuronsRaphe neuronsRat dorsal raphe neuronsCell bodiesOutward currentsInhibitory effectGalanin-like immunoreactivityDorsal raphe nucleusDose-dependent hyperpolarizationExtracellular potassium concentrationGalaninergic mechanismsSitu hybridization studiesGalanin receptorsRaphe nucleusSynaptic contactsNerve endingsPostsynaptic receptorsSoma levelGalaninImmunohistochemical analysisR2 receptorsGalanin R1NeuronsMood regulationPhysiological concentrations
1995
Galanin induces a hyperpolarization of norepinephrine-containing locus coeruleus neurons in the brainstem slice
Pieribone VA, Xu Z, Zhang X, Grillner S, Bartfai T, Hökfelt T. Galanin induces a hyperpolarization of norepinephrine-containing locus coeruleus neurons in the brainstem slice. Neuroscience 1995, 64: 861-874. PMID: 7538638, DOI: 10.1016/0306-4522(94)00450-j.Peer-Reviewed Original ResearchConceptsLocus coeruleus neuronsCoeruleus neuronsLocus coeruleusNet outward currentGalanin responseOutward currentsATP-sensitive potassium channelsNorepinephrine-containing locus coeruleus neuronsCoexistence of galaninEffects of galaninPotassium concentrationExtracellular potassium concentrationEndogenous galaninGalanin applicationNormal potassium concentrationGalanin effectsGalanin immunoreactivityBrainstem slicesNorepinephrine neuronsAxonal originLow calcium mediumNeuronal somataSlice preparationImmunohistochemical stainingGalanin