2024
Protocol for the Catheter-Related Early Thromboprophylaxis With Enoxaparin (CRETE) Studies.
Faustino E, Kandil S, Leroue M, Sochet A, Kong M, Cholette J, Nellis M, Pinto M, Chegondi M, Ramirez M, Schreiber H, Kerris E, Glau C, Kolmar A, Muisyo T, Sharathkumar A, Polikoff L, Silva C, Ehrlich L, Navarro O, Spinella P, Raffini L, Taylor S, McPartland T, Shabanova V. Protocol for the Catheter-Related Early Thromboprophylaxis With Enoxaparin (CRETE) Studies. Pediatric Critical Care Medicine 2024 PMID: 39560771, DOI: 10.1097/pcc.0000000000003648.Peer-Reviewed Original ResearchRandomized clinical trialsDose of enoxaparinCatheter-relatedEarly thromboprophylaxisHigher risk of clinically relevant bleedingRisk of clinically relevant bleedingProphylactic doses of enoxaparinTherapeutic dose of enoxaparinOlder childrenMarkers of thrombin generationClinically relevant bleedingEfficacy of prophylaxisDeep venous thrombosisRemoval of CVCsCritically ill childrenPlatelet-poor plasmaPost hoc analysisGestational ageInternational unitsInstitutional review boardRelevant bleedingProphylactic doseUsual careAge-dependent heterogeneityVenous thrombosis
2023
Inflammation Sub-Group Analysis in Pediatric HA-VTE Cases: A Report from the Children's Hospital Acquired Thrombosis Registry (CHAT) Registry
Harp T, Proctor K, Mosha M, Cox A, Jaffray J, Stillings A, Krava E, Amankwah E, Faustino E, Zakai N, Young G, Goldenberg N, Branchford B. Inflammation Sub-Group Analysis in Pediatric HA-VTE Cases: A Report from the Children's Hospital Acquired Thrombosis Registry (CHAT) Registry. Blood 2023, 142: 4015. DOI: 10.1182/blood-2023-190491.Peer-Reviewed Original ResearchPast medical historyInflammatory disease diagnosisHA-VTEDischarge diagnosisSystemic inflammationChronic inflammationAcute inflammationInflammatory diseasesOdds ratioCentral venous catheter placementAdmission/transferDays of dischargeLong-term morbidityVenous catheter placementOrgan system involvementPediatric patient populationType of inflammationClinical research effortsSub-group analysisUnderlying risk factorsInstitutional review boardElectronic health recordsChronic varietyHospital stayVenous thromboembolism