2021
Achieving Histologic Normalization in Ulcerative Colitis Is Associated With a Reduced Risk of Subsequent Dysplasia
Shaffer S, Erondu A, Traboulsi C, Rai V, Cleveland N, Israel A, Christensen B, Rubin D. Achieving Histologic Normalization in Ulcerative Colitis Is Associated With a Reduced Risk of Subsequent Dysplasia. Inflammatory Bowel Diseases 2021, 28: 553-559. PMID: 34037230, PMCID: PMC9122749, DOI: 10.1093/ibd/izab130.Peer-Reviewed Original ResearchConceptsPersistent histologic activityHistologic normalizationUlcerative colitisHistologic activityUC diagnosisSubsequent dysplasiaIncidence rateDysplasia developmentDiagnosis of UCCox regression analysisKaplan-Meier graphsImproved clinical outcomesDevelopment of dysplasiaHistologic inflammationUC durationDysplasia ratesDisease courseTertiary centerClinical outcomesDecreased riskPatient groupSurveillance intervalsHistologic assessmentRetrospective analysisReduced risk
2019
Follow-Up of Patients With Ulcerative Colitis and Histological Normalization
Israel A, Christensen B, El Jurdi K, Rai V, Ollech J, Cohen R, Sakuraba A, Dalal S, Rubin D. Follow-Up of Patients With Ulcerative Colitis and Histological Normalization. Clinical Gastroenterology And Hepatology 2019, 18: 987-988.e1. PMID: 31228567, PMCID: PMC6923607, DOI: 10.1016/j.cgh.2019.06.025.Peer-Reviewed Original ResearchMeSH KeywordsColitis, UlcerativeColonoscopyEndoscopyFollow-Up StudiesHumansInflammationIntestinal MucosaConceptsUlcerative colitisManagement of UCSpecific treatment goalsEndoscopic improvementHistological normalizationDisease activityMucosal injuryRemitting courseHistological endpointsTreatment goalsNatural historyColitisMicroscopic featuresUnanswered questionsInflammationPatientsChronicityMucosaInjuryHistologyDiagnosisEndpoint