Outcomes of Ileoanal Pouch Anastomosis in Pediatric Ulcerative Colitis Are Worse in the Modern Era: A Time Trend Analysis Outcomes Following Ileal Pouch–Anal Anastomosis in Pediatric Ulcerative Colitis
Runde J, Erondu A, Akiyama S, Traboulsi C, Rai V, Glick L, Yi Y, Ollech J, Cohen R, Skowron K, Hurst R, Umanskiy K, Shogan B, Hyman N, Rubin M, Dalal S, Sakuraba A, Pekow J, Chang E, Rubin D. Outcomes of Ileoanal Pouch Anastomosis in Pediatric Ulcerative Colitis Are Worse in the Modern Era: A Time Trend Analysis Outcomes Following Ileal Pouch–Anal Anastomosis in Pediatric Ulcerative Colitis. Inflammatory Bowel Diseases 2022, 28: 1386-1394. PMID: 35040964, PMCID: PMC9434476, DOI: 10.1093/ibd/izab319.Peer-Reviewed Original ResearchConceptsIleal pouch-anal anastomosisPediatric ulcerative colitisPouch-anal anastomosisUlcerative colitisYears of agePouch survivalAdult patientsRetrospective single-center studyIleoanal pouch anastomosisAnti-TNF therapySingle-center studyKaplan-Meier curvesLog-rank testKaplan-Meier estimatesPediatric control subjectsElectronic medical recordsChi-square testPouch anastomosisPouch failureTotal proctocolectomyPediatric patientsSurgical outcomesControl subjectsMedical recordsRapid progression