2022
Histopathology of Colectomy Specimens Predicts Endoscopic Pouch Phenotype in Patients with Ulcerative Colitis
Akiyama S, Ollech J, Traboulsi C, Rai V, Glick L, Yi Y, Runde J, Olivas A, Weber C, Cohen R, Olortegui K, Hurst R, Umanskiy K, Shogan B, Rubin M, Dalal S, Sakuraba A, Pekow J, Chang E, Hart J, Hyman N, Rubin D. Histopathology of Colectomy Specimens Predicts Endoscopic Pouch Phenotype in Patients with Ulcerative Colitis. Digestive Diseases And Sciences 2022, 67: 4020-4031. PMID: 35288827, PMCID: PMC10966959, DOI: 10.1007/s10620-022-07405-y.Peer-Reviewed Original ResearchConceptsIleal pouch-anal anastomosisUlcerative colitisColectomy specimensTerminal ileal involvementCrohn's diseaseIleal involvementPouch fistulaFocal inflammationDeep inflammationLimb involvementPouch-anal anastomosisLogistic regression analysisIleostomy takedownPouch bodyPouch lossEndoscopic appearancePathology reviewMultivariable analysisHistologic featuresPoor prognosisPathological dataEndoscopic phenotypesHigh riskPatientsInflammation
2021
Identification of Risk Factors for Coexisting Sinusitis and Inflammatory Bowel Disease
Rai V, Traboulsi C, Silfen A, Ackerman M, Erondu A, Karpin J, Gulotta G, Rubin D. Identification of Risk Factors for Coexisting Sinusitis and Inflammatory Bowel Disease. Crohn's & Colitis 360 2021, 3: otab054. PMID: 35531367, PMCID: PMC9075692, DOI: 10.1093/crocol/otab054.Peer-Reviewed Original ResearchDuration of diseaseSteroid exposureChronic sinusitis diagnosisRisk of sinusitisSingle-center studyInflammatory bowel diseaseClinical trial dataLogistic regression analysisWilcoxon rank sum testRank sum testSinusitis diagnosisSubsequent sinusitisExtraintestinal manifestationsMaintenance therapyIBD diagnosisAdverse eventsBowel diseaseUC diagnosisMultivariable analysisRisk factorsSinusitisPatientsSubsequent diseaseTrial dataYounger ageEndoscopic Phenotype of the J Pouch in Patients With Inflammatory Bowel Disease: A New Classification for Pouch Outcomes
Akiyama S, Ollech J, Rai V, Glick L, Yi Y, Traboulsi C, Runde J, Cohen R, Skowron K, Hurst R, Umanskiy K, Shogan B, Hyman N, Rubin M, Dalal S, Sakuraba A, Pekow J, Chang E, Rubin D. Endoscopic Phenotype of the J Pouch in Patients With Inflammatory Bowel Disease: A New Classification for Pouch Outcomes. Clinical Gastroenterology And Hepatology 2021, 20: 293-302.e9. PMID: 33549868, PMCID: PMC8339185, DOI: 10.1016/j.cgh.2021.02.010.Peer-Reviewed Original ResearchConceptsIleal pouch-anal anastomosisDiffuse inflammationPouch excisionSignificant contributing factorLimb involvementAnti-tumor necrosis factor drugsCox proportional hazards modelPouch-anal anastomosisFuture interventional studiesInflammatory bowel diseasePattern of inflammationHand-sewn anastomosisBody mass indexClostridioides difficile infectionLog-rank testContributing factorProportional hazards modelLogistic regression analysisEndoscopic patternsExtensive colitisIleostomy takedownPouch bodyPouch survivalBowel diseaseCommon complicationTHE CLINICAL FEATURES AND PROGNOSTIC VALUE OF INFLAMMATORY POLYPS IN THE J POUCH OF PATIENTS WITH INFLAMMATORY BOWEL DISEASE TREATED BY PROCTOCOLECTOMY WITH ILEAL POUCH-ANAL ANASTOMOSIS
Akiyama S, Ollech J, Rai V, Yi Y, Traboulsi C, Glick L, Runde J, Cohen R, Hurst R, Hyman N, Dalal S, Sakuraba A, Pekow J, Rubin D. THE CLINICAL FEATURES AND PROGNOSTIC VALUE OF INFLAMMATORY POLYPS IN THE J POUCH OF PATIENTS WITH INFLAMMATORY BOWEL DISEASE TREATED BY PROCTOCOLECTOMY WITH ILEAL POUCH-ANAL ANASTOMOSIS. Inflammatory Bowel Diseases 2021, 27: s45-s45. DOI: 10.1093/ibd/izaa347.109.Peer-Reviewed Original ResearchIleal pouch-anal anastomosisInflammatory bowel diseaseAnti-TNF drugsInflammatory polypsPouch-anal anastomosisKaplan-Meier curvesJ-pouchIBD patientsPouch excisionEndoscopic findingsBowel diseaseRectal cuffDistal pouchRetrospective single-center studyCommon anatomical locationSingle-center studyLog-rank testErythema/edemaLogistic regression analysisDifferent anatomic areasRefractory colitisChronic pouchitisBackground PatientsTotal proctocolectomyIndependent predictors