2024
A Comparative Analysis of Clinical Symptoms and Modified Pouchitis Disease Activity Index Among Endoscopic Phenotypes of the J Pouch in Patients With Inflammatory Bowel Disease
Akiyama S, Cohen N, Ollech J, Traboulsi C, Rodriguez T, Rai V, Glick L, Yi Y, Runde J, Cohen R, Skowron K, Hurst R, Umanskiy K, Shogan B, Hyman N, Rubin M, Dalal S, Sakuraba A, Pekow J, Chang E, Rubin D. A Comparative Analysis of Clinical Symptoms and Modified Pouchitis Disease Activity Index Among Endoscopic Phenotypes of the J Pouch in Patients With Inflammatory Bowel Disease. Crohn's & Colitis 360 2024, 6: otae045. PMID: 39347443, PMCID: PMC11438232, DOI: 10.1093/crocol/otae045.Peer-Reviewed Original ResearchModified Pouchitis Disease Activity IndexPouchitis Disease Activity IndexInflammatory bowel diseasePouch-related fistulasDisease activity indexEndoscopic phenotypesComparative analysis of clinical symptomsInflammatory phenotypeClinical symptomsFocal inflammationAfferent limbComplete-case analysisBowel diseaseAnalysis of clinical symptomsActivity indexInflammatory bowel disease patientsAssess symptomsComplete-caseIncomplete emptyingPouch bodyNormal pouchEndoscopic findingsDiagnosing pouchitisDiffuse inflammationPerianal symptomsEndoscopic Normalization and Transition of J-Pouch Phenotypes Over Time in Patients With Inflammatory Bowel Disease
Akiyama S, Ollech J, Cohen N, Traboulsi C, Rai V, Glick L, Yi Y, Runde J, Cohen R, Olortegui K, Hurst R, Umanskiy K, Shogan B, Hyman N, Rubin M, Dalal S, Sakuraba A, Pekow J, Chang E, Rubin D. Endoscopic Normalization and Transition of J-Pouch Phenotypes Over Time in Patients With Inflammatory Bowel Disease. Inflammatory Bowel Diseases 2024, izae106. PMID: 38916136, DOI: 10.1093/ibd/izae106.Peer-Reviewed Original ResearchPouch-related fistulasInflammatory bowel diseaseNormal pouchDiffuse inflammationFocal inflammationAfferent limbBowel diseaseAssociated with favorable outcomesIleal pouch-anal anastomosisPouch-anal anastomosisPouch lossEndoscopic phenotypesIleostomy takedownFavorable outcomePouch inflammationPouch excisionPouch phenotypesPrimary phenotypeFistulaEndoscopic classificationInflammationPatientsPouch bodyCuffitisPhenotypic transition
2021
Identification of Risk Factors for Coexisting Sinusitis and Inflammatory Bowel Disease
Rai V, Traboulsi C, Silfen A, Ackerman M, Erondu A, Karpin J, Gulotta G, Rubin D. Identification of Risk Factors for Coexisting Sinusitis and Inflammatory Bowel Disease. Crohn's & Colitis 360 2021, 3: otab054. PMID: 35531367, PMCID: PMC9075692, DOI: 10.1093/crocol/otab054.Peer-Reviewed Original ResearchDuration of diseaseSteroid exposureChronic sinusitis diagnosisRisk of sinusitisSingle-center studyInflammatory bowel diseaseClinical trial dataLogistic regression analysisWilcoxon rank sum testRank sum testSinusitis diagnosisSubsequent sinusitisExtraintestinal manifestationsMaintenance therapyIBD diagnosisAdverse eventsBowel diseaseUC diagnosisMultivariable analysisRisk factorsSinusitisPatientsSubsequent diseaseTrial dataYounger ageEndoscopic Phenotype of the J Pouch in Patients With Inflammatory Bowel Disease: A New Classification for Pouch Outcomes
Akiyama S, Ollech J, Rai V, Glick L, Yi Y, Traboulsi C, Runde J, Cohen R, Skowron K, Hurst R, Umanskiy K, Shogan B, Hyman N, Rubin M, Dalal S, Sakuraba A, Pekow J, Chang E, Rubin D. Endoscopic Phenotype of the J Pouch in Patients With Inflammatory Bowel Disease: A New Classification for Pouch Outcomes. Clinical Gastroenterology And Hepatology 2021, 20: 293-302.e9. PMID: 33549868, PMCID: PMC8339185, DOI: 10.1016/j.cgh.2021.02.010.Peer-Reviewed Original ResearchConceptsIleal pouch-anal anastomosisDiffuse inflammationPouch excisionSignificant contributing factorLimb involvementAnti-tumor necrosis factor drugsCox proportional hazards modelPouch-anal anastomosisFuture interventional studiesInflammatory bowel diseasePattern of inflammationHand-sewn anastomosisBody mass indexClostridioides difficile infectionLog-rank testContributing factorProportional hazards modelLogistic regression analysisEndoscopic patternsExtensive colitisIleostomy takedownPouch bodyPouch survivalBowel diseaseCommon complicationTHE CLINICAL FEATURES AND PROGNOSTIC VALUE OF INFLAMMATORY POLYPS IN THE J POUCH OF PATIENTS WITH INFLAMMATORY BOWEL DISEASE TREATED BY PROCTOCOLECTOMY WITH ILEAL POUCH-ANAL ANASTOMOSIS
Akiyama S, Ollech J, Rai V, Yi Y, Traboulsi C, Glick L, Runde J, Cohen R, Hurst R, Hyman N, Dalal S, Sakuraba A, Pekow J, Rubin D. THE CLINICAL FEATURES AND PROGNOSTIC VALUE OF INFLAMMATORY POLYPS IN THE J POUCH OF PATIENTS WITH INFLAMMATORY BOWEL DISEASE TREATED BY PROCTOCOLECTOMY WITH ILEAL POUCH-ANAL ANASTOMOSIS. Gastroenterology 2021, 160: s61-s62. DOI: 10.1053/j.gastro.2021.01.158.Peer-Reviewed Original ResearchTHE CLINICAL FEATURES AND PROGNOSTIC VALUE OF INFLAMMATORY POLYPS IN THE J POUCH OF PATIENTS WITH INFLAMMATORY BOWEL DISEASE TREATED BY PROCTOCOLECTOMY WITH ILEAL POUCH-ANAL ANASTOMOSIS
Akiyama S, Ollech J, Rai V, Yi Y, Traboulsi C, Glick L, Runde J, Cohen R, Hurst R, Hyman N, Dalal S, Sakuraba A, Pekow J, Rubin D. THE CLINICAL FEATURES AND PROGNOSTIC VALUE OF INFLAMMATORY POLYPS IN THE J POUCH OF PATIENTS WITH INFLAMMATORY BOWEL DISEASE TREATED BY PROCTOCOLECTOMY WITH ILEAL POUCH-ANAL ANASTOMOSIS. Inflammatory Bowel Diseases 2021, 27: s45-s45. DOI: 10.1093/ibd/izaa347.109.Peer-Reviewed Original ResearchIleal pouch-anal anastomosisInflammatory bowel diseaseAnti-TNF drugsInflammatory polypsPouch-anal anastomosisKaplan-Meier curvesJ-pouchIBD patientsPouch excisionEndoscopic findingsBowel diseaseRectal cuffDistal pouchRetrospective single-center studyCommon anatomical locationSingle-center studyLog-rank testErythema/edemaLogistic regression analysisDifferent anatomic areasRefractory colitisChronic pouchitisBackground PatientsTotal proctocolectomyIndependent predictorsSARS-CoV-2 vaccination for patients with inflammatory bowel diseases: recommendations from an international consensus meeting
Siegel C, Melmed G, McGovern D, Rai V, Krammer F, Rubin D, Abreu M, Dubinsky M, Ahuja V, Allez M, Ananthakrishnan A, Bernstein C, Braun J, Chowers Y, Colombel J, Danese S, Dignass A, Dotan I, Fleshner P, Gasche C, Gearry R, Ghosh S, Griffiths A, Hanauer S, Hart A, Kaplan G, Kaser A, Kotze P, Koutroubakis I, Kruis W, Lakatos P, Levine A, Lewis J, Lindsay J, Loftus E, Louis E, Lukas M, Magro F, Mahadevan U, Mantzaris G, Moum B, Munkholm P, Ng S, O’Morain C, Oresland T, Panaccione R, Panes J, Pemberton J, Prantera C, Ran Z, Reinisch W, Rogler G, Sandborn W, Sands B, Sartor B, Schölmerich J, Siegmund B, Silverberg M, Sood A, Spinelli A, Steinwurz F, Travis S, Turner D, Tysk C, Vatn M, Vermeire S, Yamamoto T, Yamamoto-Furusho J, Panis Y. SARS-CoV-2 vaccination for patients with inflammatory bowel diseases: recommendations from an international consensus meeting. Gut 2021, 70: 635-640. PMID: 33472895, PMCID: PMC7818789, DOI: 10.1136/gutjnl-2020-324000.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAssessment of Comorbid Depression and Anxiety in Inflammatory Bowel Disease Using Adaptive Testing Technology
Karpin J, Rodriguez T, Traboulsi C, Rai V, Gibbons R, Rubin D. Assessment of Comorbid Depression and Anxiety in Inflammatory Bowel Disease Using Adaptive Testing Technology. Crohn's & Colitis 360 2021, 3: otaa095. PMID: 34746788, PMCID: PMC8570563, DOI: 10.1093/crocol/otaa095.Peer-Reviewed Original ResearchInflammatory bowel diseaseBowel diseaseExact testActive inflammatory bowel diseaseClinical remission statusNegative CRP valuesMental health screeningPearson's chi-square testFisher's exact testMental health conditionsChi-square testCAT-MHIBD clinicIBD patientsPositive CRPUndiagnosed anxietyClinical remissionDisease activityIBD populationPatient characteristicsConsecutive patientsCRP valuesMultivariable analysisSignificant positive associationRemission status
2020
Pouchitis in inflammatory bowel disease: a review of diagnosis, prognosis, and treatment
Akiyama S, Rai V, Rubin D. Pouchitis in inflammatory bowel disease: a review of diagnosis, prognosis, and treatment. Intestinal Research 2020, 19: 1-11. PMID: 33138344, PMCID: PMC7873408, DOI: 10.5217/ir.2020.00047.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsIleal pouch-anal anastomosisInflammatory bowel diseaseBowel diseaseRisk factorsUlcerative colitis patientsPouch-anal anastomosisReview of diagnosisDysplasia/cancerNew biological agentsPouchitis developmentRefractory colitisColitis patientsPouch failureRestorative proctocolectomyPouch excisionCrohn's diseaseImpairs qualityTreatment optionsChronic conditionsPouchitisFrequent reasonPatientsDiseaseProctocolectomyPrognosisBlack Race and Public Insurance Are Predictive of Inappropriate Evaluation of Iron Deficiency Anemia and Diarrhea
Anyane-Yeboa A, Li B, Traboulsi C, Erondu A, Sossenheimer P, Rai V, Rubin D. Black Race and Public Insurance Are Predictive of Inappropriate Evaluation of Iron Deficiency Anemia and Diarrhea. Digestive Diseases And Sciences 2020, 66: 2200-2206. PMID: 32638203, DOI: 10.1007/s10620-020-06434-9.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseIron deficiency anemiaAge-adjusted multivariate analysisAppropriate workupChronic diarrheaCeliac diseaseBlack raceDeficiency anemiaDiagnosis codesInsurance statusMultivariate analysisPublic insurancePublic insurance statusChronic disease statesChicago Medical CenterMethodsMedical recordsBowel diseaseResultsIn totalMedical CenterDiarrheaWorkupIron deficiencyLogistic regressionPatientsSeparate encounters