A salt bridge of the C‐terminal carboxyl group regulates PHPT1 substrate affinity and catalytic activity
Zavala E, Dansereau S, Burke M, Lipchock J, Maschietto F, Batista V, Loria J. A salt bridge of the C‐terminal carboxyl group regulates PHPT1 substrate affinity and catalytic activity. Protein Science 2024, 33: e5009. PMID: 38747379, PMCID: PMC11094782, DOI: 10.1002/pro.5009.Peer-Reviewed Original ResearchConceptsCatalytic activityPhenylphosphonic acidAnalysis of molecular dynamics trajectoriesNMR chemical shiftsSalt bridgesMolecular dynamics trajectoriesC-terminal carboxyl groupChemical shiftsCombination of solution NMRMolecular dynamicsGuanidinium moietyCarboxyl groupsPara-nitrophenylphosphateSolution NMRActive site inhibitorsHistidine phosphataseActive siteElectrostatic interactionsDynamics trajectoriesEnzymatic functionC-terminusGlycine residuesSubstrate affinityBiochemical experimentsBinding affinityDehydrogenation and Transfer Hydrogenation of Alkenones to Phenols and Ketones on Carbon-Supported Noble Metals
Li K, Kelly H, Franco A, Batista V, Baráth E. Dehydrogenation and Transfer Hydrogenation of Alkenones to Phenols and Ketones on Carbon-Supported Noble Metals. ACS Catalysis 2024, 14: 2883-2896. PMID: 38449532, PMCID: PMC10913045, DOI: 10.1021/acscatal.3c04849.Peer-Reviewed Original ResearchKeto-enol tautomerismCatalytic materialsPresence of hydrogen donorsSelection of catalytic materialsSaturated cyclic ketonesM-O bondsNoble metal catalystsBond distance changesAromatic compoundsEntropy of activationBalance of enthalpyTransfer hydrogenationCyclic ketonesMetal catalystsCatalytic dehydrogenationDienolate intermediateDehydrogenation reactionM-OCyclic alcoholsNoble metalsCatalytic activityHydrogen donorBinding orientationEnonesTautomerismPhotoelectrochemical Urea Synthesis from Nitrate and Carbon Dioxide on GaN Nanowires
Dong W, Menzel J, Ye Z, Navid I, Zhou P, Yang K, Batista V, Mi Z. Photoelectrochemical Urea Synthesis from Nitrate and Carbon Dioxide on GaN Nanowires. ACS Catalysis 2024, 14: 2588-2596. DOI: 10.1021/acscatal.3c04264.Peer-Reviewed Original ResearchAg cocatalystC-N couplingReversible hydrogen electrodeSemiconductor photoelectrodesFaradaic efficiencyHydrogen electrodeReduction reactionSolar lightCatalytic activityGaN nanowiresTheoretical calculationsCocatalystCarbon dioxideOptimal conditionsNanowiresSynthesisConversion to nitriteSelectivity of ureaSynthesize ureaPhotoelectrodePhotoelectrochemicalDioxideUreaNitrateControl experiments