2021
Latent brain state dynamics and cognitive flexibility in older adults
Lee B, Cai W, Young CB, Yuan R, Ryman S, Kim J, Santini V, Henderson VW, Poston KL, Menon V. Latent brain state dynamics and cognitive flexibility in older adults. Progress In Neurobiology 2021, 208: 102180. PMID: 34627994, PMCID: PMC9585912, DOI: 10.1016/j.pneurobio.2021.102180.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAgingBayes TheoremBrainCognitionHumansMagnetic Resonance ImagingMemory, Short-TermMiddle AgedConceptsBrain flexibilityOlder adultsBrain statesWhole-brain fMRI dataBrain state dynamicsHealthy older adultsCognitive flexibilityMemory taskCognitive inflexibilityNeurocomputational frameworkCognitive deficitsFMRI dataCognitive impairmentDynamic temporal propertiesInflexibilityAdultsTemporal propertiesPublic health concernCognitionSternbergElderly populationHealth concernTaskDeficitsImpairment
2019
Three-year follow-up of prospective trial of focused ultrasound thalamotomy for essential tremor.
Halpern CH, Santini V, Lipsman N, Lozano AM, Schwartz ML, Shah BB, Elias WJ, Cosgrove GR, Hayes MT, McDannold N, Aldrich C, Eisenberg HM, Gandhi D, Taira T, Gwinn R, Ro S, Witt J, Jung NY, Chang JW, Rosenberg J, Ghanouni P. Three-year follow-up of prospective trial of focused ultrasound thalamotomy for essential tremor. Neurology 2019, 93: e2284-e2293. PMID: 31748250, DOI: 10.1212/wnl.0000000000008561.Peer-Reviewed Original ResearchConceptsFocused ultrasound thalamotomyAdverse eventsQuality of lifeEssential tremorProspective trialUltrasound thalamotomyMedication-refractory essential tremorTcMRgFUS thalamotomyMulticenter prospective trialNew adverse eventsClass IV evidenceHand tremorEssential Tremor QuestionnaireSevere essential tremorClinical rating scalesMagnetic resonance-guided focused ultrasound thalamotomyClinical outcomesFunctional disabilityThird followTreatment metricsTremor scorePostural tremorDurable benefitThalamotomyMedian score
2009
Chronic Traumatic Encephalopathy in Athletes: Progressive Tauopathy After Repetitive Head Injury
McKee AC, Cantu RC, Nowinski CJ, Hedley-Whyte ET, Gavett BE, Budson AE, Santini VE, Lee HS, Kubilus CA, Stern RA. Chronic Traumatic Encephalopathy in Athletes: Progressive Tauopathy After Repetitive Head Injury. Journal Of Neuropathology & Experimental Neurology 2009, 68: 709-735. PMID: 19535999, PMCID: PMC2945234, DOI: 10.1097/nen.0b013e3181a9d503.Peer-Reviewed Original ResearchConceptsChronic traumatic encephalopathyTraumatic encephalopathyProgressive tauopathyTau-immunoreactive neurofibrillary tanglesRepetitive brain traumaRepetitive head injuryProgressive neurological deteriorationCavum septum pellucidumSuperficial cortical layersMedial temporal lobeAstrocytic tanglesTau-immunoreactiveNeurological deteriorationDementia pugilisticaVentricular dilatationBrain traumaHead injurySeptum pellucidumNeurofibrillary degenerationMammillary bodiesNeurofibrillary tanglesDiffuse plaquesGait abnormalitiesMemory disturbanceTemporal lobe
2008
Clock drawing performance in cognitively normal elderly
Hubbard EJ, Santini V, Blankevoort CG, Volkers KM, Barrup MS, Byerly L, Chaisson C, Jefferson AL, Kaplan E, Green RC, Stern RA. Clock drawing performance in cognitively normal elderly. Archives Of Clinical Neuropsychology 2008, 23: 295-327. PMID: 18243644, PMCID: PMC2752157, DOI: 10.1016/j.acn.2007.12.003.Peer-Reviewed Original Research