Race/ethnicity and socioeconomic status as predictors of outcome following family therapy in youth at clinical high risk for psychosis
Ruiz‐Yu B, Le T, Weintraub M, Zinberg J, Addington J, O'Brien M, Walsh B, Friedman‐Yakoobian M, Auther A, Cornblatt, Domingues I, Cannon T, Miklowitz D, Bearden C. Race/ethnicity and socioeconomic status as predictors of outcome following family therapy in youth at clinical high risk for psychosis. Early Intervention In Psychiatry 2024 PMID: 38676463, PMCID: PMC11512687, DOI: 10.1111/eip.13541.Peer-Reviewed Original ResearchClinical high riskNegative symptomsFamily therapyRandomized trial of family-focused therapyGlobal functioningEffect of race/ethnicityNHW participantsTrial of family therapyFamily-focused therapyParental educationAssociated with greater improvementSociodemographic factorsSocioeconomic statusPositive symptomsPsychosocial treatmentsPsychosocial functioningHigher parental educationFollow-up measurementsHigh riskInfluence of race/ethnicityGreater improvementRandomized trialsTreatment outcomesPsychosisPredictors of outcomeDifferential expression of haptoglobin in individuals at clinical high risk of psychosis and its association with global functioning and clinical symptoms
Healy C, Byrne J, Raj Suasi S, Föcking M, Mongan D, Kodosaki E, Heurich M, Cagney G, Wynne K, Bearden C, Woods S, Cornblatt B, Mathalon D, Stone W, Cannon T, Addington J, Cadenhead K, Perkins D, Jeffries C, Cotter D. Differential expression of haptoglobin in individuals at clinical high risk of psychosis and its association with global functioning and clinical symptoms. Brain Behavior And Immunity 2024, 117: 175-180. PMID: 38219978, DOI: 10.1016/j.bbi.2023.12.018.Peer-Reviewed Original ResearchGlobal Assessment of Functioning ScaleNorth American Prodrome Longitudinal StudyClinical high riskPoor functionScale of Psychosis-risk SymptomsPsychosis-risk symptomsAssociated with poorer functioningFirst-episode psychosisTransition to psychosisGreater symptom severityFollow-upIndividuals at-riskClinical symptomsPsychotic disordersHigh riskSymptom severityPsychosocial functioningGlobal functioningPsychosisSubscale scoresFDR correctionAcute phase inflammatory responseLongitudinal studyGlobal assessmentFunctional scales