2024
Signal integration and adaptive sensory diversity tuning in Escherichia coli chemotaxis
Moore J, Kamino K, Kottou R, Shimizu T, Emonet T. Signal integration and adaptive sensory diversity tuning in Escherichia coli chemotaxis. Cell Systems 2024, 15: 628-638.e8. PMID: 38981486, PMCID: PMC11307269, DOI: 10.1016/j.cels.2024.06.003.Peer-Reviewed Original ResearchEscherichia coli chemotaxisPopulation of E. coliMeasure kinase activityPhenotypic diversitySensory diversityDecreased diversityKinase activityDiverse phenotypesChemical signalsDiversitySingle cellsResponse to changesCellsSignalPhenotypePopulationChemotaxisSignal integrityLigandCompetitive ligandChemoattractant
2022
Collective behavior and nongenetic inheritance allow bacterial populations to adapt to changing environments
Mattingly H, Emonet T. Collective behavior and nongenetic inheritance allow bacterial populations to adapt to changing environments. Proceedings Of The National Academy Of Sciences Of The United States Of America 2022, 119: e2117377119. PMID: 35727978, PMCID: PMC9245662, DOI: 10.1073/pnas.2117377119.Peer-Reviewed Original ResearchConceptsNongenetic inheritanceCollective migrationPhenotype compositionIsogenic populationsDifferential lossSwimming phenotypeCell divisionBacterial populationsCell growthMultiple environmentsPhenotypePhenotypic compositionDifferent phenotypesInheritanceChemotactic bacteriaModel systemHigh inheritanceMigration speedDifferent environmentsNew environmentCollective behaviorMigrationPopulationGrowthDiversity
2020
Adaptive tuning of cell sensory diversity without changes in gene expression
Kamino K, Keegstra JM, Long J, Emonet T, Shimizu TS. Adaptive tuning of cell sensory diversity without changes in gene expression. Science Advances 2020, 6: eabc1087. PMID: 33188019, PMCID: PMC7673753, DOI: 10.1126/sciadv.abc1087.Peer-Reviewed Original ResearchConceptsPhenotypic diversityGene expressionCell variationDiversity of phenotypesChemoreceptor TarPosttranslational modificationsAllosteric couplingEnvironmental cuesChemotaxis networkCovalent modificationEnvironmental changesDiversitySensory diversityCell populationsCellsExpressionSuch betsPhenotypeEscherichiaPopulationPrevious studiesModificationVariationSignalsChemoreceptors