2024
Emergency Department Visits Among Patients With Dementia Before and After Diagnosis
Gettel C, Song Y, Rothenberg C, Kitchen C, Gilmore-Bykovskyi A, Fried T, Brody A, Nothelle S, Wolff J, Venkatesh A. Emergency Department Visits Among Patients With Dementia Before and After Diagnosis. JAMA Network Open 2024, 7: e2439421. PMID: 39401040, DOI: 10.1001/jamanetworkopen.2024.39421.Peer-Reviewed Original Research
2023
Validation of Electronic Health Record-Based Algorithms to Identify Specialist Palliative Care Within the Department of Veterans Affairs
Feder S, Zhan Y, Abel E, Smith D, Ersek M, Fried T, Redeker N, Akgün K. Validation of Electronic Health Record-Based Algorithms to Identify Specialist Palliative Care Within the Department of Veterans Affairs. Journal Of Pain And Symptom Management 2023, 66: e475-e483. PMID: 37364737, PMCID: PMC10527602, DOI: 10.1016/j.jpainsymman.2023.06.023.Peer-Reviewed Original ResearchConceptsSpecialist palliative careInpatient encountersCurrent Procedural TerminologyPalliative careICD-9/ICDICD-9/10 codesCohort of peopleVeterans Affairs facilitiesStop codeNegative predictive valueElectronic health recordsChart reviewHeart failureAdministrative databasesSpecific clinicPredictive valueICD codesProcedural TerminologyVeterans AffairsOutpatientsHealth recordsAdministrative dataReference standardCareConsultation
2022
Effect of Computer-Tailored Print Feedback, Motivational Interviewing, and Motivational Enhancement Therapy on Engagement in Advance Care Planning
Fried T, Yang M, Martino S, Iannone L, Zenoni M, Blakley L, O’Leary J, Redding C, Paiva A. Effect of Computer-Tailored Print Feedback, Motivational Interviewing, and Motivational Enhancement Therapy on Engagement in Advance Care Planning. JAMA Internal Medicine 2022, 182: 1298-1305. PMID: 36342678, PMCID: PMC9641591, DOI: 10.1001/jamainternmed.2022.5074.Peer-Reviewed Original ResearchConceptsAdvance care planningMotivational enhancement therapyMotivational interviewingUsual careClinical trialsCare planningEnhancement therapySingle VA facilityPrimary care visitsPrimary care patientsList of patientsSelf-administered toolClinician-led approachQuantity of lifeACP activityHealth care agentSelf-reported completionOversampling of womenElectronic health recordsCare visitsCare patientsTelephone contactOlder veteransMAIN OUTCOMETelephone assessment
2021
Effect of the STAMP (Sharing and Talking About My Preferences) Intervention on Completing Multiple Advance Care Planning Activities in Ambulatory Care : A Cluster Randomized Controlled Trial.
Fried TR, Paiva AL, Redding CA, Iannone L, O'Leary JR, Zenoni M, Risi MM, Mejnartowicz S, Rossi JS. Effect of the STAMP (Sharing and Talking About My Preferences) Intervention on Completing Multiple Advance Care Planning Activities in Ambulatory Care : A Cluster Randomized Controlled Trial. Annals Of Internal Medicine 2021, 174: 1519-1527. PMID: 34461035, PMCID: PMC8711627, DOI: 10.7326/m21-1007.Peer-Reviewed Original ResearchConceptsAdvance care planning activitiesCare planning activitiesAmbulatory care settingsAdvance care planningCare planningCare settingsNon-English speaking participantsSpecialty care practicesUsual care sitesPrespecified subgroup analysisPatient sociodemographic informationNational InstituteParticipant-level analysesQuantity of lifeHealth care agentSecondary outcomesUsual carePrimary outcomeControlled TrialsMean ageSubgroup analysisBlinded interviewersAmbulatory careCare sitesPrint interventionPrognostic information, goals of care, and code status decision‐making among older patients
van Dyck L, Fried TR. Prognostic information, goals of care, and code status decision‐making among older patients. Journal Of The American Geriatrics Society 2021, 69: 2025-2028. PMID: 33675032, PMCID: PMC8273121, DOI: 10.1111/jgs.17080.Peer-Reviewed Original Research
2019
Medication Appropriateness in Vulnerable Older Adults: Healthy Skepticism of Appropriate Polypharmacy
Fried TR, Mecca MC. Medication Appropriateness in Vulnerable Older Adults: Healthy Skepticism of Appropriate Polypharmacy. Journal Of The American Geriatrics Society 2019, 67: 1123-1127. PMID: 30697698, PMCID: PMC6561813, DOI: 10.1111/jgs.15798.Peer-Reviewed Original ResearchConceptsNumber of medicationsAppropriate polypharmacyOlder adultsMedication benefitsComplex medication regimensMultiple chronic conditionsVulnerable older adultsMedication appropriatenessUnderestimate harmsInappropriate medicationsMore medicationsAdverse eventsMore observational studiesMedication regimensComplex regimenAdverse outcomesAppropriate medicationChronic conditionsMedications resultsObservational studyPolypharmacyMedicationsHealth outcomesCorrect medicationLikelihood of harm
2011
Effects of Benefits and Harms on Older Persons' Willingness to Take Medication for Primary Cardiovascular Prevention
Fried TR, Tinetti ME, Towle V, O’Leary J, Iannone L. Effects of Benefits and Harms on Older Persons' Willingness to Take Medication for Primary Cardiovascular Prevention. JAMA Internal Medicine 2011, 171: 923-928. PMID: 21357797, PMCID: PMC3101287, DOI: 10.1001/archinternmed.2011.32.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAspirinCardiotonic AgentsCardiovascular DiseasesDrug-Related Side Effects and Adverse ReactionsFemaleHealth Knowledge, Attitudes, PracticeHumansInterviews as TopicMaleMyocardial InfarctionPatient CompliancePatient ParticipationPatient SelectionPharmaceutical PreparationsPrimary PreventionRisk AssessmentSurveys and QuestionnairesConceptsPrimary cardiovascular disease preventionCardiovascular disease preventionMyocardial infarctionAbsolute benefitAdverse effectsDisease preventionOlder personsCommunity-living older personsPrimary cardiovascular preventionEvidence-based guidelinesAverage risk reductionRisk reductionCardiovascular preventionAvailable medicationsPrimary preventionClinical guidelinesTreatment benefitMild fatigueMedicationsQuality assurance initiativesPerson interviewsPreventionParticipantsHarmLarge proportion
2010
Primary Care Clinicians' Experiences With Treatment Decision Making for Older Persons With Multiple Conditions
Fried TR, Tinetti ME, Iannone L. Primary Care Clinicians' Experiences With Treatment Decision Making for Older Persons With Multiple Conditions. JAMA Internal Medicine 2010, 171: 75-80. PMID: 20837819, PMCID: PMC3021478, DOI: 10.1001/archinternmed.2010.318.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedChronic DiseaseComorbidityConnecticutDecision MakingFemaleFocus GroupsGoalsHospitals, UniversityHumansMaleMedication AdherenceMiddle AgedNarrationNurse PractitionersPatient CompliancePhysician AssistantsPhysicians, Primary CarePractice Patterns, Physicians'Primary Health CareQualitative ResearchResidence CharacteristicsUnited StatesWorkforceConceptsGuideline-directed carePrimary care cliniciansTreatment decisionsOlder patientsCare cliniciansOlder personsDisease-specific guidelinesMultiple medical conditionsPrimary care practicesBetter treatment decisionsComplex regimensPatient goalsPatient prioritiesPatient's abilityClinician experienceMedical conditionsOutcome dataPatientsCare practicesVeterans AffairsMultiple conditionsCliniciansDesign of interventionsRole of specialistsMultiple diseasesElectronic health records and adverse drug events after patient transfer
Boockvar K, Livote E, Goldstein N, Nebeker J, Siu A, Fried T. Electronic health records and adverse drug events after patient transfer. BMJ Quality & Safety 2010, 19: e16. PMID: 20724395, PMCID: PMC2965207, DOI: 10.1136/qshc.2009.033050.Peer-Reviewed Original ResearchConceptsAdverse drug eventsHigh-risk medication discrepanciesElectronic health recordsMedication discrepanciesSite of careDrug eventsPatient transferStructured medical record reviewNon-VA groupsNon-VA patientsVeterans Affairs patientsHealth recordsMedical record reviewGroup of patientsPairs of physiciansHospitalisation episodesMedication reviewHospital transferOverall incidenceRecord reviewClinical covariatesMedication errorsNursing homesPatientsTime of transfer
2002
Understanding the Treatment Preferences of Seriously Ill Patients
Fried TR, Bradley EH, Towle VR, Allore H. Understanding the Treatment Preferences of Seriously Ill Patients. New England Journal Of Medicine 2002, 346: 1061-1066. PMID: 11932474, DOI: 10.1056/nejmsa012528.Peer-Reviewed Original ResearchConceptsBurden of treatmentTreatment preferencesAdverse outcomesCognitive impairmentChronic obstructive pulmonary diseaseLow-burden treatmentCongestive heart failureObstructive pulmonary diseaseSevere functional impairmentLimited life expectancyOutcome of treatmentAdvance care planningYears of agePercent of participantsLife-sustaining treatmentHeart failureIll patientsPulmonary diseaseQuestions patientsPatient preferencesPrimary diagnosisPatients' attitudesFunctional impairmentHigh burdenCare planning
2001
Documentation of discussions about prognosis with terminally ill patients
Bradley E, Hallemeier A, Fried T, Johnson-Hurzeler R, Cherlin E, Kasl S, Horwitz S. Documentation of discussions about prognosis with terminally ill patients. The American Journal Of Medicine 2001, 111: 218-223. PMID: 11530033, DOI: 10.1016/s0002-9343(01)00798-7.Peer-Reviewed Original ResearchConceptsIll patientsMedical recordsDocumentation of discussionInoperable lung cancerStandardized abstraction formAdvance care planningLife-sustaining treatmentEnd of lifeClinical factorsMedical chartsIll inpatientsLung cancerCommunity hospitalResuscitate ordersAbstraction formCare planningGall bladderPatientsPrognosisFuture careFamily preferencesInpatientsCancerTreatmentPrevious studies
1999
Older persons’ perceptions of home and hospital as sites of treatment for acute illness
Fried T, van Doorn C, O’Leary J, Tinetti M, Drickamer M. Older persons’ perceptions of home and hospital as sites of treatment for acute illness. The American Journal Of Medicine 1999, 107: 317-323. PMID: 10527032, DOI: 10.1016/s0002-9343(99)00236-3.Peer-Reviewed Original ResearchConceptsAcute illnessChronic obstructive pulmonary diseasePersons age 65 yearsCongestive heart failureObstructive pulmonary diseaseHome careAge 65 yearsOlder patients' perceptionsEfficacy of treatmentAcute home careSite of treatmentSelf-rated healthPatient characteristicsHeart failurePulmonary diseaseAcute careHospital treatmentDependent patientsPrimary diagnosisPatients' perceptionsHome treatmentUse of homeHospital careOlder persons' perceptionsHospitalOlder persons' preferences for site of terminal care.
Fried T, Doorn C, O'Leary J, Tinetti M, Drickamer M. Older persons' preferences for site of terminal care. Annals Of Internal Medicine 1999, 131: 109-12. PMID: 10419426, DOI: 10.7326/0003-4819-131-2-199907200-00006.Peer-Reviewed Original ResearchConceptsTerminal careOlder persons' preferencesCommunity-dwelling persons 65 yearsChronic obstructive pulmonary diseaseCongestive heart failureObstructive pulmonary diseasePersons 65 yearsSite of careLong-term care needsCare of disabilitiesFamily membersNonterminal illnessHeart failurePulmonary diseaseQuantitative interviewsPatient preferencesLife careCare needsNursing homesQualitative interviewsTerminal illnessParticipants' homesOlder personsHospitalCareWho Dies at Home? Determinants of Site of Death for Community‐Based Long‐Term Care Patients
Fried T, Pollack D, Drickamer M, Tinetti M. Who Dies at Home? Determinants of Site of Death for Community‐Based Long‐Term Care Patients. Journal Of The American Geriatrics Society 1999, 47: 25-29. PMID: 9920226, DOI: 10.1111/j.1532-5415.1999.tb01897.x.Peer-Reviewed Original ResearchConceptsSite of deathInpatient hospiceLong-term care patientsCommunity-based long-term care programsDependent functional statusPatients 65 yearsChronic lung diseaseCoronary artery diseaseYear of admissionCommunity-based long-term careLong-term care programsLong-term careCohort studyArtery diseaseCare patientsHome deathLung diseaseFunctional statusPatient preferencesHomecare patientsFemale genderTerminal careMAIN OUTCOMECare needsNursing homes
1998
Older Persons’ Preferences for Site of Treatment in Acute Illness. ANNOUNCEMENT
Fried T, Van Doorn C, Tinetti M, Drickamer M. Older Persons’ Preferences for Site of Treatment in Acute Illness. ANNOUNCEMENT. Journal Of General Internal Medicine 1998, 13: 522-527. PMID: 9734788, PMCID: PMC1496998, DOI: 10.1046/j.1525-1497.1998.00162.x.Peer-Reviewed Original ResearchConceptsAcute illnessHome care servicesHome treatmentHome careCare servicesChronic obstructive pulmonary diseaseCongestive heart failureObstructive pulmonary diseaseProcess of careLower intensity servicesSite of treatmentOlder persons' preferencesPersons age 65Health care systemHeart failurePulmonary diseasePatient preferencesHospital careMedical careAge 65Older personsHospitalIllness experienceCare systemCareFactors Associated With Six‐Month Mortality in Recipients of Community‐Based Long‐Term Care
Fried T, Pollack D, Tinetti M. Factors Associated With Six‐Month Mortality in Recipients of Community‐Based Long‐Term Care. Journal Of The American Geriatrics Society 1998, 46: 193-197. PMID: 9475448, DOI: 10.1111/j.1532-5415.1998.tb02538.x.Peer-Reviewed Original ResearchConceptsSix-month mortalityShort-term mortalityPresence of cancerCommunity-based long-term careLong-term careHeart diseaseChronic obstructive pulmonary diseaseNutritional problemsObstructive pulmonary diseaseSevere cognitive impairmentCommunity-based waiverCohort studyPulmonary diseaseHomecare programMortality registryMale sexFunctional impairmentClinical dataAdmission assessmentRoutine assessmentCognitive impairmentHealth statusMultivariate analysisCognitive statusMortalityMODELS OF GERIATRICS PRACTICE: When the Patient Cannot Come to the Doctor: A Medical Housecalls Program
Reuben D, Fried T, Wachtel T, Tinetti M. MODELS OF GERIATRICS PRACTICE: When the Patient Cannot Come to the Doctor: A Medical Housecalls Program. Journal Of The American Geriatrics Society 1998, 46: 226-231. PMID: 9475454, DOI: 10.1111/j.1532-5415.1998.tb02544.x.Peer-Reviewed Original ResearchConceptsUpper respiratory tract infectionFrail older patientsRespiratory tract infectionsCongestive heart failureMajority of patientsRoutine medical careSevere cognitive impairmentGERIATRICS PRACTICEAcute illnessOlder patientsTract infectionsHeart failureHomebound patientsUnscheduled visitsEmergency roomNurse practitionersDaily livingMedical residency programsPatientsPatient's homeScheduled visitsAmbulatory practiceCognitive impairmentComplex illnessMedical care
1997
Frailty and Hospitalization of Long‐Term Stay Nursing Home Residents
Fried T, Mor V. Frailty and Hospitalization of Long‐Term Stay Nursing Home Residents. Journal Of The American Geriatrics Society 1997, 45: 265-269. PMID: 9063269, DOI: 10.1111/j.1532-5415.1997.tb00938.x.Peer-Reviewed Original ResearchConceptsCongestive heart failurePrimary diagnosisNursing homesHeart failureRespiratory diseaseRecent functional declineNursing home patientsSevere functional impairmentCertain patient groupsNursing home stayNursing home residentsProprietary nursing homesLower ratesLogistic regression modelsCohort studyAcute careHome patientsHospitalization ratesPatient groupFeeding tubeDecubitus ulcersFunctional impairmentHome residentsFunctional declineHospitalizationShort‐Term Functional Outcomes of Long‐Term Care Residents with Pneumonia Treated with and without Hospital Transfer
Fried T, Gillick M, Lipsitz L. Short‐Term Functional Outcomes of Long‐Term Care Residents with Pneumonia Treated with and without Hospital Transfer. Journal Of The American Geriatrics Society 1997, 45: 302-306. PMID: 9063275, DOI: 10.1111/j.1532-5415.1997.tb00944.x.Peer-Reviewed Original ResearchConceptsResolution of pneumoniaHospital transferHospital treatmentFunctional statusLong-term care facility patientsRespiratory rateLong-term care residentsCare facility patientsIndependent functional statusRetrospective cohort studyCases of pneumoniaTerm functional outcomesFunctional status outcomesHebrew Rehabilitation CenterAcademic medical centerLogistic regression modelsLower respiratory rateNew infiltratesLTCF residentsAcute episodeCohort studyFacility patientsSevere pneumoniaFunctional outcomeRespiratory signs
1996
The association between age of hospitalized patients and the delivery of advanced cardiac life support
Fried T, Miller M, Stein M, Wachtel T. The association between age of hospitalized patients and the delivery of advanced cardiac life support. Journal Of General Internal Medicine 1996, 11: 257-261. PMID: 8725973, DOI: 10.1007/bf02598264.Peer-Reviewed Original ResearchConceptsAdvanced cardiac life supportCardiac life supportLife supportDependent functional statusIndividual patient characteristicsUrban teaching hospitalLogistic regression modelsElectromechanical dissociationRetrospective cohortHospitalized patientsPatient characteristicsAdult inpatientsCardiopulmonary arrestACLS protocolFunctional statusElectrocardiographic rhythmTeaching hospitalVentricular fibrillationNonsurvivorsBedside determinationOlder agePatientsShort trialTrialsMedical services