Collapsin response mediator protein‐2 phosphorylation promotes the reversible retraction of oligodendrocyte processes in response to non‐lethal oxidative stress
Fernández‐Gamba A, Leal M, Maarouf C, Richter‐Landsberg C, Wu T, Morelli L, Roher A, Castaño E. Collapsin response mediator protein‐2 phosphorylation promotes the reversible retraction of oligodendrocyte processes in response to non‐lethal oxidative stress. Journal Of Neurochemistry 2012, 121: 985-995. PMID: 22443207, PMCID: PMC3371108, DOI: 10.1111/j.1471-4159.2012.07742.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntioxidantsBlotting, WesternFluorescent Antibody TechniqueHumansImmunohistochemistryIntercellular Signaling Peptides and ProteinsMutagenesis, Site-DirectedNerve Tissue ProteinsOligodendrogliaOxidative StressPhosphorylationPolymerase Chain ReactionRatsRats, WistarReactive Oxygen SpeciesSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationTransfectionConceptsNon-lethal oxidative stressOxidative stressCollapsin response mediator protein 2 (CRMP2) phosphorylationOLN-93 cellsCRMP-2Collapsin response mediator protein 2Response mediator protein 2Rho-kinaseWhite matter pathologyCandidate effector moleculesProtein 2 phosphorylationVehicle-exposed cellsCell line cellsAxonal contactHuman dementiaAdult brainNeurodegenerative conditionsProcess retractionOligodendrocytesEndogenous reactive oxygen speciesReactive oxygen speciesPrimary oligodendrocytesPrecursor cellsExtension of processesEffector molecules