A Pilot Study on the Proteomics Profile of Serum Exosome-Enriched Extracellular Vesicles from Normal versus Individuals with Obesity-Related Insulin Resistance
Saraswathi V, Ai W, Kumar V, Sharma K, Gopal T, Kumar N, Malhi H, Sehrawat T, Desouza C. A Pilot Study on the Proteomics Profile of Serum Exosome-Enriched Extracellular Vesicles from Normal versus Individuals with Obesity-Related Insulin Resistance. Biomedicines 2024, 12: 799. PMID: 38672154, PMCID: PMC11048419, DOI: 10.3390/biomedicines12040799.Peer-Reviewed Original ResearchObesity-related insulin resistanceIngenuity Pathway AnalysisInsulin resistanceB cellsRegulate immune cell activationSerum exosomesImmune cell activationIsolated serum exosomesB cell activationRisk of diabetesHigh-risk individualsExosome-enriched extracellular vesiclesProteomic profilingProgression of diabetesIngenuity Pathway Analysis analysesCell activationInsulin sensitivityProtein expressionOB-IRExosomal proteinsTherapeutic targetMale subjectsExtracellular vesiclesExtracellular spaceInflammation