Gonadotropin Activity during Early Folliculogenesis and Implications for Polycystic Ovarian Syndrome and Premature Ovarian Insufficiency: A Narrative Review
Longobardi S, Klinger F, Zheng W, Campitiello M, D’Hooghe T, La Marca A. Gonadotropin Activity during Early Folliculogenesis and Implications for Polycystic Ovarian Syndrome and Premature Ovarian Insufficiency: A Narrative Review. International Journal Of Molecular Sciences 2024, 25: 7520. PMID: 39062762, PMCID: PMC11277126, DOI: 10.3390/ijms25147520.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromePremature ovarian insufficiencyFollicle-stimulating hormoneEarly folliculogenesisOvarian reservePolycystic ovarian syndromeOvarian insufficiencyLuteinizing hormoneOvarian syndromePool of primordial folliclesFemale fertilityPrimordial follicle activationPrimordial follicle developmentStages of folliculogenesisResponse to gonadotropinsMolecular pathway alterationsInfluence of LHYears of ageGonadotropin-independentGonadotropin-dependentPrimordial folliclesAntral stageAntiepileptic treatmentPathway alterationsFolliculogenesis