Therapeutic management in women with a diminished ovarian reserve: a systematic review and meta-analysis of randomized controlled trials
Conforti A, Carbone L, Di Girolamo R, Iorio G, Guida M, Campitiello M, Ubaldi F, Rienzi L, Vaiarelli A, Cimadomo D, Ronsini C, Longobardi S, D'Hooghe T, Esteves S, Alviggi C. Therapeutic management in women with a diminished ovarian reserve: a systematic review and meta-analysis of randomized controlled trials. Fertility And Sterility 2024 PMID: 39332623, DOI: 10.1016/j.fertnstert.2024.09.038.Peer-Reviewed Original ResearchDiminished ovarian reserveLive birth rateOvarian reserveRandomized controlled trialsClinical management of womenHigher live birth ratesAssociated with higher live birth ratesMeta-analysis of randomized controlled trialsControlled trialsInvestigate adjuvant treatmentsManagement of womenLow-dose gonadotropinsLuteal phase stimulationBirth ratePOSEIDON criteriaCorifollitropin alfaAdjuvant treatmentGonadotropin regimensGnRH antagonistClomiphene citrateLuteinizing hormoneTherapeutic managementTestosterone supplementationClinical managementRandomized trialsGonadotropin Activity during Early Folliculogenesis and Implications for Polycystic Ovarian Syndrome and Premature Ovarian Insufficiency: A Narrative Review
Longobardi S, Klinger F, Zheng W, Campitiello M, D’Hooghe T, La Marca A. Gonadotropin Activity during Early Folliculogenesis and Implications for Polycystic Ovarian Syndrome and Premature Ovarian Insufficiency: A Narrative Review. International Journal Of Molecular Sciences 2024, 25: 7520. PMID: 39062762, PMCID: PMC11277126, DOI: 10.3390/ijms25147520.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromePremature ovarian insufficiencyFollicle-stimulating hormoneEarly folliculogenesisOvarian reservePolycystic ovarian syndromeOvarian insufficiencyLuteinizing hormoneOvarian syndromePool of primordial folliclesFemale fertilityPrimordial follicle activationPrimordial follicle developmentStages of folliculogenesisResponse to gonadotropinsMolecular pathway alterationsInfluence of LHYears of ageGonadotropin-independentGonadotropin-dependentPrimordial folliclesAntral stageAntiepileptic treatmentPathway alterationsFolliculogenesis