2022
Extracellular Vesicles Mediate the Intercellular Exchange of Nanoparticles
Wu X, Tang T, Wei Y, Cummins K, Wood D, Pang H. Extracellular Vesicles Mediate the Intercellular Exchange of Nanoparticles. Advanced Science 2022, 9: 2102441. PMID: 35243822, PMCID: PMC8895114, DOI: 10.1002/advs.202102441.Peer-Reviewed Original ResearchConceptsIntercellular exchangeExtracellular vesiclesComplex tissuesImportance of EVsCell-cell contactTranscellular transport routeDirect cell-cell contactSubcellular transportNP endocytosisExocytosisAccumulative evidenceVesiclesSame receptorCrucial rolePotential mechanismsCellsTransport routesEndocytosisTissueSignificant fractionTransportVitroAssaysVivoReceptors
2019
Tumor-specific macrophage targeting through recognition of retinoid X receptor beta
Tang T, Wei Y, Kang J, She Z, Kim D, Sailor M, Ruoslahti E, Pang H. Tumor-specific macrophage targeting through recognition of retinoid X receptor beta. Journal Of Controlled Release 2019, 301: 42-53. PMID: 30871996, PMCID: PMC6500479, DOI: 10.1016/j.jconrel.2019.03.009.Peer-Reviewed Original ResearchConceptsRetinoid X receptor betaTumor macrophagesSystemic administrationReceptor betaNormal macrophage functionCancer therapyTumor-bearing miceTumor-selective bindingCell surface markersNovel cell surface markersMacrophage modulationMacrophage functionSolid tumorsTumor-specific mannerMacrophage typesSurface markersMacrophagesCancer progressionTumorsHealthy organsNuclear receptorsTherapyAdministrationCell surface localizationReceptors