Rapid chelator-free radiolabeling of quantum dots for in vivo imaging
Tang T, Wei Y, Yang Q, Yang Y, Sailor M, Pang H. Rapid chelator-free radiolabeling of quantum dots for in vivo imaging. Nanoscale 2019, 11: 22248-22254. PMID: 31746913, DOI: 10.1039/c9nr08508d.Peer-Reviewed Original ResearchConceptsChelator-free radiolabelingQuantum dotsZinc sulfide quantum dotsSulfide quantum dotsNanoparticle surfaceSurface functionalizationAqueous solutionHigh labeling efficiencyMetal chelationCation exchangeRadiolabeling approachChemical propertiesCellular uptakeMetal chelatorsLabeling efficiencyDotsVivo PET imagingHigh tumor uptakeMurine cancer modelsRadiochemical purityRadiolabelingNanoparticlesFunctionalizationChelatorsChelationCellular internalization of bystander nanomaterial induced by TAT-nanoparticles and regulated by extracellular cysteine
Wei Y, Tang T, Pang H. Cellular internalization of bystander nanomaterial induced by TAT-nanoparticles and regulated by extracellular cysteine. Nature Communications 2019, 10: 3646. PMID: 31409778, PMCID: PMC6692393, DOI: 10.1038/s41467-019-11631-w.Peer-Reviewed Original ResearchConceptsCargo selectivityExtracellular cysteinesCysteine regulationNP entryCellular activitiesMacropinocytosis pathwayCellular uptakeAmino acidsCargoCellular internalizationInternalizationTAT peptideNanomaterial deliveryCellsUptakeVivoEndocytosisIntensive studyCysteinePathwayRegulationActivityPeptidesEntry