2022
Extracellular Vesicles Mediate the Intercellular Exchange of Nanoparticles
Wu X, Tang T, Wei Y, Cummins K, Wood D, Pang H. Extracellular Vesicles Mediate the Intercellular Exchange of Nanoparticles. Advanced Science 2022, 9: 2102441. PMID: 35243822, PMCID: PMC8895114, DOI: 10.1002/advs.202102441.Peer-Reviewed Original ResearchConceptsIntercellular exchangeExtracellular vesiclesComplex tissuesImportance of EVsCell-cell contactTranscellular transport routeDirect cell-cell contactSubcellular transportNP endocytosisExocytosisAccumulative evidenceVesiclesSame receptorCrucial rolePotential mechanismsCellsTransport routesEndocytosisTissueSignificant fractionTransportVitroAssaysVivoReceptors
2019
Cellular internalization of bystander nanomaterial induced by TAT-nanoparticles and regulated by extracellular cysteine
Wei Y, Tang T, Pang H. Cellular internalization of bystander nanomaterial induced by TAT-nanoparticles and regulated by extracellular cysteine. Nature Communications 2019, 10: 3646. PMID: 31409778, PMCID: PMC6692393, DOI: 10.1038/s41467-019-11631-w.Peer-Reviewed Original ResearchConceptsCargo selectivityExtracellular cysteinesCysteine regulationNP entryCellular activitiesMacropinocytosis pathwayCellular uptakeAmino acidsCargoCellular internalizationInternalizationTAT peptideNanomaterial deliveryCellsUptakeVivoEndocytosisIntensive studyCysteinePathwayRegulationActivityPeptidesEntry