1995
Metabolic Effects of IGF-I: Implications for the Therapy of Diabetes Mellitus
Sherwin R, Borg W, Boulware S. Metabolic Effects of IGF-I: Implications for the Therapy of Diabetes Mellitus. Serono Symposia USA 1995, 195-203. DOI: 10.1007/978-1-4612-0807-5_18.Peer-Reviewed Original ResearchNonsuppressible insulin-like activityInsulin-like activityMetabolic effectsInsulin-like growth factor IGrowth factor IAction of GHDiabetes mellitusImmunoreactive insulinSomatomedin CFactor IBiologic activityInsulinFurther studiesSomatic growthMellitusIGFSomatomedinTherapyActivityRadioimmunoassayGHSerum
1989
Increased insulin secretion in puberty: A compensatory response to reductions in insulin sensitivity
Caprio S, Plewe G, Diamond M, Simonson D, Boulware S, Sherwin R, Tamborlane W. Increased insulin secretion in puberty: A compensatory response to reductions in insulin sensitivity. The Journal Of Pediatrics 1989, 114: 963-967. PMID: 2524556, DOI: 10.1016/s0022-3476(89)80438-x.Peer-Reviewed Original ResearchConceptsInsulin secretionPlasma insulinInsulin sensitivityInsulin-like growth factor IC-peptide responseGlucose-stimulated insulin secretionC-peptide concentrationsExcessive insulin secretionHyperglycemic clamp techniqueGlucose clamp procedureGrowth factor IGlucose incrementClamp procedureHealthy childrenPlasma levelsInsulin responseHyperglycemic stimulusClamp techniqueInsulin actionFactor INormal adultsNormal childrenCompensatory responseInsulinPuberty