1992
Effect of growth hormone treatment on hyperinsulinemia associated with turner syndrome
Caprio S, Boulware S, Press M, Sherwin R, Rubin K, Carpenter T, Plewe G, Tamborlane W. Effect of growth hormone treatment on hyperinsulinemia associated with turner syndrome. The Journal Of Pediatrics 1992, 120: 238-243. PMID: 1735819, DOI: 10.1016/s0022-3476(05)80434-2.Peer-Reviewed Original ResearchConceptsControl subjectsGrowth hormoneTurner syndromeHyperinsulinemic responseInsulin responseHyperglycemic glucose clamp techniqueSecond-phase insulin responseInsulin-stimulated glucose metabolismGlucose-stimulated insulin responseMonths of therapyMonths of treatmentTotal cholesterol levelsExcessive insulin secretionGrowth hormone treatmentGlucose clamp techniqueGlucose clamp procedureHuman growth hormoneBlood pressureGlucose incrementGlycosylated hemoglobinInsulin resistancePlasma levelsCholesterol levelsClamp procedureHealthy children
1991
Does Insulin Species Modify Counterregulatory Hormone Response to Hypoglycemia?
Jones T, Caprio S, Diamond M, Hallarman L, Boulware S, Sherwin R, Tamborlane W. Does Insulin Species Modify Counterregulatory Hormone Response to Hypoglycemia? Diabetes Care 1991, 14: 728-731. PMID: 1954809, DOI: 10.2337/diacare.14.8.728.Peer-Reviewed Original ResearchConceptsPlasma glucoseInsulin levelsHormonal responsesSteady-state insulin levelsCounterregulatory hormone levelsCounterregulatory hormone responsesHuman insulinHuman regular insulinGlucose clamp techniqueHealthy young adultsCounterregulatory responsesHypoglycemic stimulusRegular insulinInsulin administrationHormone levelsHealthy adultsHormone responseGrowth hormoneHypoglycemiaYoung adultsInsulinSignificant differencesGlucoseAdultsResponseIndependent Effects of Youth and Poor Diabetes Control on Responses to Hypoglycemia in Children
Jones T, Boulware S, Kraemer D, Caprio S, Sherwin R, Tamborlane W. Independent Effects of Youth and Poor Diabetes Control on Responses to Hypoglycemia in Children. Diabetes 1991, 40: 358-363. PMID: 1999278, DOI: 10.2337/diab.40.3.358.Peer-Reviewed Original ResearchConceptsInsulin-dependent diabetes mellitusSymptom awarenessNondiabetic childrenPlasma glucoseGlucose thresholdHormone releaseGlucose levelsCounterregulatory hormone levelsCounterregulatory hormone releasePoor diabetes controlGlucose clamp techniqueGrowth hormone releasePlasma glucose levelsEffects of childhoodCounterregulatory hormonesEpinephrine responseNondiabetic adultsYounger patientsDiabetes mellitusEpinephrine releaseSymptom scoresDiabetes controlPlasma epinephrineSymptomatic responseMild hypoglycemia