2023
Early pregnancy metabolic syndrome and risk for adverse pregnancy outcomes: findings from Rajarata Pregnancy Cohort (RaPCo) in Sri Lanka
Jayasinghe I, Agampodi T, Dissanayake A, Agampodi S. Early pregnancy metabolic syndrome and risk for adverse pregnancy outcomes: findings from Rajarata Pregnancy Cohort (RaPCo) in Sri Lanka. BMC Pregnancy And Childbirth 2023, 23: 231. PMID: 37020187, PMCID: PMC10074348, DOI: 10.1186/s12884-023-05548-y.Peer-Reviewed Original ResearchConceptsGestational agePreterm birthPregnancy outcomesPregnant womenMetabolic syndromePregnancy cohortJoint Interim Statement criteriaFirst trimester pregnant womenMajor pregnancy outcomesSouth Asian pregnant womenAdverse pregnancy outcomesNeonatal birth weightGestational weight gainMedian gestational ageProspective cohort studyLive singleton birthsSignificant risk predictorAsian pregnant womenConclusionPregnant womenFPG thresholdMetS prevalenceCohort studyCumulative incidenceProspective cohortMetS definitions
2022
The geo-spatial perspective of biological, social and environmental determinants of early pregnancy anaemia in rural Sri Lanka: Need for context-specific approaches on prevention
Amarasinghe G, Agampodi T, Mendis V, Agampodi S. The geo-spatial perspective of biological, social and environmental determinants of early pregnancy anaemia in rural Sri Lanka: Need for context-specific approaches on prevention. Geospatial Health 2022, 17 PMID: 36468596, DOI: 10.4081/gh.2022.1110.Peer-Reviewed Original ResearchConceptsPrevalence of anemiaEarly pregnancyPregnant womenRisk factorsFirst trimester pregnant womenHigher anemia prevalenceAntenatal care programsEnvironmental risk factorsHeterogeneous risk factorsMaternal anemiaPregnancy anemiaPregnancy cohortAnemia prevalenceDietary patternsHigh prevalenceAnemiaCare programRural Sri LankaPrevalenceSocioeconomic disparitiesPregnancyHealth DivisionEthnic distributionSignificant differencesAnuradhapura districtFactors associated with early pregnancy anemia in rural Sri Lanka: Does being ‘under care’ iron out socioeconomic disparities?
Amarasinghe G, Agampodi T, Mendis V, Agampodi S. Factors associated with early pregnancy anemia in rural Sri Lanka: Does being ‘under care’ iron out socioeconomic disparities? PLOS ONE 2022, 17: e0274642. PMID: 36201463, PMCID: PMC9536542, DOI: 10.1371/journal.pone.0274642.Peer-Reviewed Original ResearchConceptsPregnancy anemiaPregnant womenFirst trimester pregnant womenSocioeconomic disparitiesRisk of anemiaOdds of anemiaFull blood countHistory of anemiaContinuum of carePeriod of gestationFamily Health ProgramHierarchical logistic regression modelsSelf-completed questionnaireLogistic regression modelsHealth care coveragePublic health infrastructureMaternal anemiaAntenatal careCohort studyBreast feedingContraceptive injectionMiddle-income countriesAnemia preventionRegression modelsAnemia controlFatty Liver Index is a valid predictor of non-alcoholic fatty liver disease (NAFLD) in pregnancy
Koralegedara IS, Warnasekara JN, Rathnayake A, Dayaratne KG, Agampodi SB. Fatty Liver Index is a valid predictor of non-alcoholic fatty liver disease (NAFLD) in pregnancy. BMJ Open Gastroenterology 2022, 9: e000913. PMID: 35728866, PMCID: PMC9214354, DOI: 10.1136/bmjgast-2022-000913.Peer-Reviewed Original ResearchConceptsNon-alcoholic fatty liver diseaseFatty liver indexAdverse pregnancy outcomesFatty liver diseasePregnant womenPregnancy outcomesLiver diseaseFatty liverLiver indexFirst trimester pregnant womenGamma-glutamyl transferase levelsBody mass indexPeriod of gestationLogistic regression modelsBinary logistic regression modelIndependent predictorsMass indexPregnancy cohortEarly pregnancyMean ageTransferase levelsLiver enzymesUltrasound scanGeneral populationHealth setupDoes Being Diagnosed As Anemic in Early Pregnancy Have an Impact on the Household Expenditure for Food? Evidence From a Maternal Cohort in Rural Sri Lanka
Gunarathne S, Amarasinghe G, Agampodi T, Wickramasinghe N, Mendis V, Prasanna I, Agampodi S. Does Being Diagnosed As Anemic in Early Pregnancy Have an Impact on the Household Expenditure for Food? Evidence From a Maternal Cohort in Rural Sri Lanka. Current Developments In Nutrition 2022, 6: 654. PMCID: PMC9193294, DOI: 10.1093/cdn/nzac061.038.Peer-Reviewed Original ResearchNon-anaemic womenEarly pregnancyPregnant womenRural Sri LankaFirst trimester pregnant womenPublic health midwivesHousehold food expenditureThird of pregnanciesAnemic pregnant womenMann-Whitney U testDiagnosis of anemiaMonthly household incomeLifestyle modificationHemoglobin levelsPregnancy cohortThird trimesterMean ageModerate anemiaMaternal cohortAppropriate treatmentHousehold economic statusNutritional educationSelf-administrated questionnairePregnancyAnemiaNon-alcoholic fatty liver disease (NAFLD): a significant predictor of gestational diabetes mellitus (GDM) and early pregnancy miscarriages—prospective study in Rajarata Pregnancy Cohort (RaPCo)
Koralegedara IS, Warnasekara JN, Dayaratne KG, De Silva FN, Premadasa JK, Agampodi SB. Non-alcoholic fatty liver disease (NAFLD): a significant predictor of gestational diabetes mellitus (GDM) and early pregnancy miscarriages—prospective study in Rajarata Pregnancy Cohort (RaPCo). BMJ Open Gastroenterology 2022, 9: e000831. PMID: 35193889, PMCID: PMC8867246, DOI: 10.1136/bmjgast-2021-000831.Peer-Reviewed Original ResearchConceptsNon-alcoholic fatty liver diseaseGestational diabetes mellitusEarly pregnancy miscarriageFatty liver diseasePregnancy miscarriageRisk factorsDiabetes mellitusLiver diseasePregnant womenRelative riskEffect of NAFLDImpact of NAFLDPopulation-based prospective cohort studyRepeat oral glucose tolerance testFirst trimester pregnant womenOral glucose tolerance testPregnancy care programsProspective cohort studyOnly independent predictorBody mass indexGlucose tolerance testWeeks of gestationSignificant risk factorsMajor risk factorHigh-risk mothersPrevalence and aetiologies of anaemia among first trimester pregnant women in Sri Lanka; the need for revisiting the current control strategies
Amarasinghe GS, Agampodi TC, Mendis V, Malawanage K, Kappagoda C, Agampodi SB. Prevalence and aetiologies of anaemia among first trimester pregnant women in Sri Lanka; the need for revisiting the current control strategies. BMC Pregnancy And Childbirth 2022, 22: 16. PMID: 34986796, PMCID: PMC8734253, DOI: 10.1186/s12884-021-04341-z.Peer-Reviewed Original ResearchConceptsFirst trimester pregnant womenFull blood countPregnant womenAnemic womenBlood countRobust public health infrastructureIron deficiencyPeripheral blood film examinationFull blood count analysisEtiology of anemiaMultiple micronutrient supplementationTrimester pregnant womenAnemic pregnant womenBlood count analysisBlood film examinationPublic health interventionsPositive predictive valueForms of malnutritionMaternal care programmeRed cell countRed cell indicesMiddle-income settingsPublic health infrastructureSerum B12B12 deficiency