2024
A review on polyamines as promising next-generation neuroprotective and anti-aging therapy
Arthur R, Jamwal S, Kumar P. A review on polyamines as promising next-generation neuroprotective and anti-aging therapy. European Journal Of Pharmacology 2024, 978: 176804. PMID: 38950837, DOI: 10.1016/j.ejphar.2024.176804.Peer-Reviewed Original ResearchCognitive dysfunctionNeurodegenerative disordersRegulation of gene expressionProgressive degeneration of neuronsProgrammed cell deathDegeneration of neuronsSymptomatic therapyPharmacological strategiesAnti-oxidative effectsAnti-aging therapyAverage ageProgressive degenerationNeuroprotective effectsLocomotor abnormalitiesIon channelsCell deathBiochemical activityGene expressionPopulation average ageTherapyMolecular mechanismsDisordersPolyamine supplementationDysfunctionAnti-aging effects
2017
Animal Model of Amyotrophic Lateral Sclerosis
Koshal P, Kumar M, Jamwal S, Bansal P. Animal Model of Amyotrophic Lateral Sclerosis. 2017, 277-289. DOI: 10.1007/978-981-10-5981-0_18.Peer-Reviewed Original ResearchAmyotrophic lateral sclerosisMotor neuronsLateral sclerosisMuscle performancePatients of ALSPrevalence of ALSCases of ALSDepletion of neuronsUpper motor neuronsLower motor neuronsFamilial amyotrophic lateral sclerosisInvolvement of neuronsLou Gehrig's diseaseALS-dementiaCerebral cortexMuscle weaknessSubstantia nigraBrain stemDisease progressionSpinal cordMuscle atrophyAnimal modelsAverage ageCognitive impairmentNeurodegenerative disorders