DECIPHERING THE UNDERLYING BIOLOGY OF PSYCHIATRIC DISORDERS THROUGH LONGITUDINAL FAMILY COHORT BASED STUDIES IN INDIA
Viswanath B, Sud R, Ganesh S, Mahadevan J, Holla B, Paul P, Purushottam M, Jain S, Consortium A. DECIPHERING THE UNDERLYING BIOLOGY OF PSYCHIATRIC DISORDERS THROUGH LONGITUDINAL FAMILY COHORT BASED STUDIES IN INDIA. European Neuropsychopharmacology 2024, 87: 43-44. DOI: 10.1016/j.euroneuro.2024.08.108.Peer-Reviewed Original ResearchAdverse childhood eventsWhole-exome sequencingFirst-degree relativesChildhood eventsStudies of psychiatric disordersFamily history densityObsessive compulsive disorderGenetic studies of psychiatric disordersSubstance use disordersPeripheral blood mononuclear cellsSevere mental illnessLongitudinal family cohortGenetic studiesAge-of-onsetTransdiagnostic endophenotypesBrain imaging abnormalitiesCompulsive disorderBipolar disorderPsychiatric diagnosisPsychiatric disordersMultiple affected membersCognitive performanceRare damaging variantsMental illnessCognitive AssessmentW32. A GENOME-WIDE ASSOCIATION STUDY OF BIPOLAR DISORDER FROM INDIA
Mahadevan J, Holla B, Ganesh S, Shankarappa B, Paul P, Sud R, Jain S, Purushottam M, Viswanath B. W32. A GENOME-WIDE ASSOCIATION STUDY OF BIPOLAR DISORDER FROM INDIA. European Neuropsychopharmacology 2024, 87: 118. DOI: 10.1016/j.euroneuro.2024.08.241.Peer-Reviewed Original ResearchGenome-wide association studiesGenomic risk lociRisk lociAssociation studiesGenome-wide association study of BDGenome wide association studiesAncestry principal componentsSevere mental illnessWhole-genome sequencingTissue expression analysisBiology of BdPatients of European ancestryBipolar disorderHRC panelGenome sequenceMental illnessAncestry samplesGenomic methodsEpisodes of depressionAllele dosageGenetic studiesEuropean ancestryICD-10Outpatient clinicTrained psychiatrists