1991
Calcium channel antagonists and human immunodeficiency virus coat protein–mediated neuronal injury
Lipton S. Calcium channel antagonists and human immunodeficiency virus coat protein–mediated neuronal injury. Annals Of Neurology 1991, 30: 110-114. PMID: 1656845, DOI: 10.1002/ana.410300121.Peer-Reviewed Original ResearchConceptsVoltage-dependent calcium channelsCalcium channel antagonistsNeuronal injuryChannel antagonistsCalcium channelsHuman immunodeficiency virus type 1 (HIV-1) envelope proteinImmunodeficiency syndrome dementia complexRat retinal ganglion cellsSubsequent neuronal injuryNeuronal calcium channelsRetinal ganglion cellsVoltage-dependent Ca2Mammalian central neuronsChannel antagonist drugsNeuronal damageDementia complexMaximal doseCentral neuronsGanglion cellsDihydropyridine classIntracellular calciumAntagonist drugsElectrophysiological studiesLow micromolar concentrationsGp120
1989
Calcium channels in solitary retinal ganglion cells from post‐natal rat.
Karschin A, Lipton S. Calcium channels in solitary retinal ganglion cells from post‐natal rat. The Journal Of Physiology 1989, 418: 379-396. PMID: 2559971, PMCID: PMC1189978, DOI: 10.1113/jphysiol.1989.sp017847.Peer-Reviewed Original ResearchConceptsRetinal ganglion cellsWhole-cell recordingsCalcium currentGanglion cellsOmega-conotoxin fraction GVIAT-type calcium currentL-type calcium currentDorsal root ganglion neuronesCell-attached patch recordingsDihydropyridine agonist Bay K8644Agonist Bay K8644Central mammalian neuronesPost-natal ratsSingle-channel patch-clamp techniquesPatch-clamp techniqueCell-attached recordingsWhole-cell currentsNeuronal membrane potentialEquimolar Ba2Reversible blockadeBay K8644T-currentsGanglion neuronesPharmacological agentsCalcium channels