1990
Neural nicotinic acetylcholine responses in sensory neurons from postnatal rat
Sucher N, Cheng T, Lipton S. Neural nicotinic acetylcholine responses in sensory neurons from postnatal rat. Brain Research 1990, 533: 248-254. PMID: 2289141, DOI: 10.1016/0006-8993(90)91346-i.Peer-Reviewed Original ResearchConceptsDRG cellsPostnatal ratsInward currentsFunctional nicotinic acetylcholine receptorsDorsal root ganglion cellsNicotinic acetylcholine responsesAgonist-induced currentsNicotinic acetylcholine receptorsPatch-clamp techniqueWhole-cell configurationAcetylcholine responseNicotinic responsesGanglion cellsNeuronal bungarotoxinNeuronal typesSensory neuronsNicotinic acetylcholineAcetylcholine receptorsNewborn animalsAcetylcholineIrreversible blockPresence of toxinsRatsCellsDMPPBlockade of nicotinic responses in rat retinal ganglion cells by neuronal bungarotoxin
Aizenman E, Loring R, Lipton S. Blockade of nicotinic responses in rat retinal ganglion cells by neuronal bungarotoxin. Brain Research 1990, 517: 209-214. PMID: 2375991, DOI: 10.1016/0006-8993(90)91028-f.Peer-Reviewed Original ResearchConceptsRat retinal ganglion cellsRetinal ganglion cellsNeuronal bungarotoxinGanglion cellsTotal blockadeFunctional nicotinic receptorsAcetylcholine-induced currentsNicotinic acetylcholine responsesNicotinic currentsAcetylcholine responseNicotinic responsesComplete blockadeNicotinic receptorsSuperfusion methodPressure ejectionToxin applicationBlockadePatch electrodeBungarotoxinCellsHigh affinityResponseReceptors
1989
Characterization of nicotinic receptors in chick retina using a snake venom neurotoxin that blocks neuronal nicotinic receptor function
Loring R, Aizenman E, Lipton, Zigmond R. Characterization of nicotinic receptors in chick retina using a snake venom neurotoxin that blocks neuronal nicotinic receptor function. Journal Of Neuroscience 1989, 9: 2423-2431. PMID: 2746336, PMCID: PMC6569765, DOI: 10.1523/jneurosci.09-07-02423.1989.Peer-Reviewed Original ResearchConceptsNicotinic receptor functionNicotinic receptorsChick retinaNicotinic agonistsReceptor functionNeuronal nicotinic receptor functionIntact chick retinaFunctional nicotinic receptorsInner plexiform layerAutonomic gangliaGanglion cellsPlexiform layerCholine acetyltransferaseNeuronal bungarotoxinNeuromuscular antagonistsNicotinic functionNeuronal preparationsRetinaAgonistsReceptorsAntagonistSnake venom neurotoxinsVenom neurotoxinsLow affinityHigh affinity