1995
An astrocytic binding site for neuronal Thy-1 and its effect on neurite outgrowth.
Dreyer E, Leifer D, Heng J, McConnell J, Gorla M, Levin L, Barnstable C, Lipton S. An astrocytic binding site for neuronal Thy-1 and its effect on neurite outgrowth. Proceedings Of The National Academy Of Sciences Of The United States Of America 1995, 92: 11195-11199. PMID: 7479964, PMCID: PMC40598, DOI: 10.1073/pnas.92.24.11195.Peer-Reviewed Original ResearchConceptsNeurite outgrowthThy-1 functionsNeuronal Thy-1Thy-1Abundant glycoproteinMammalian neuronsNervous systemAnti-idiotype monoclonal antibodyCentral nervous system neuronsMonoclonal antibodiesBinding sitesCentral nervous systemAnti-idiotype antibodiesCertain monoclonal antibodiesBinding assaysCompetitive binding assaysProteinOutgrowthSystem neuronsDendritic developmentAntibodiesNeuronsSitesGlycoproteinCells
1992
Selectivity of Thy-1 monoclonal antibodies in enhancing neurite outgrowth
Lipton S, Leifer D, Barnstable C. Selectivity of Thy-1 monoclonal antibodies in enhancing neurite outgrowth. Neuroscience Letters 1992, 137: 75-77. PMID: 1352632, DOI: 10.1016/0304-3940(92)90302-n.Peer-Reviewed Original Research
1991
Immunofluorescent characterization of retinal ganglion cell neurites cultured on substrates coated with antibodies against Thy-1
Leifer D, Dreyer E, Lipton S. Immunofluorescent characterization of retinal ganglion cell neurites cultured on substrates coated with antibodies against Thy-1. Experimental Neurology 1991, 113: 386-390. PMID: 1680742, DOI: 10.1016/0014-4886(91)90030-g.Peer-Reviewed Original ResearchConceptsRetinal ganglion cellsGanglion cellsThy-1Rat retinal ganglion cellsMicrotubule-associated protein 2Display immunoreactivityImmunofluorescent characterizationAntibodiesAxonal compartmentProtein 2Neurite outgrowthDays of cultureDendritic featuresCellsCytoskeletal proteinsImmunoreactivityCell membraneCryopreservation of postnatal rat retinal ganglion cells: Persistence of voltage- and ligand-gated ionic currents
Sucher N, Cheng T, Lipton S. Cryopreservation of postnatal rat retinal ganglion cells: Persistence of voltage- and ligand-gated ionic currents. Neuroscience 1991, 43: 135-150. PMID: 1717883, DOI: 10.1016/0306-4522(91)90423-l.Peer-Reviewed Original ResearchConceptsRetinal ganglion cellsGanglion cellsPostnatal rat retinal ganglion cellsOutward currentsRat retinal ganglion cellsCultured retinal ganglion cellsTetraethylammonium-sensitive currentPostnatal retinal ganglion cellsInhibitory amino acidsRetinal cell suspensionsWhole-cell modePatch-clamp techniqueWhole-cell configurationBicuculline methiodideMicroM tetrodotoxinChloride-selective currentsPharmacological sensitivityPotassium currentMicroM Cd2Prolonged time courseAction potentialsProlonged componentsVoltage protocolsSignificant differencesTime course