1993
Molecular mechanisms of trauma-induced neuronal degeneration.
Lipton S. Molecular mechanisms of trauma-induced neuronal degeneration. Current Opinion In Neurology 1993, 6: 588-96. PMID: 8400474.Peer-Reviewed Original Research
1991
Cryopreservation of postnatal rat retinal ganglion cells: Persistence of voltage- and ligand-gated ionic currents
Sucher N, Cheng T, Lipton S. Cryopreservation of postnatal rat retinal ganglion cells: Persistence of voltage- and ligand-gated ionic currents. Neuroscience 1991, 43: 135-150. PMID: 1717883, DOI: 10.1016/0306-4522(91)90423-l.Peer-Reviewed Original ResearchConceptsRetinal ganglion cellsGanglion cellsPostnatal rat retinal ganglion cellsOutward currentsRat retinal ganglion cellsCultured retinal ganglion cellsTetraethylammonium-sensitive currentPostnatal retinal ganglion cellsInhibitory amino acidsRetinal cell suspensionsWhole-cell modePatch-clamp techniqueWhole-cell configurationBicuculline methiodideMicroM tetrodotoxinChloride-selective currentsPharmacological sensitivityPotassium currentMicroM Cd2Prolonged time courseAction potentialsProlonged componentsVoltage protocolsSignificant differencesTime course
1990
Blockade of nicotinic responses in rat retinal ganglion cells by neuronal bungarotoxin
Aizenman E, Loring R, Lipton S. Blockade of nicotinic responses in rat retinal ganglion cells by neuronal bungarotoxin. Brain Research 1990, 517: 209-214. PMID: 2375991, DOI: 10.1016/0006-8993(90)91028-f.Peer-Reviewed Original ResearchConceptsRat retinal ganglion cellsRetinal ganglion cellsNeuronal bungarotoxinGanglion cellsTotal blockadeFunctional nicotinic receptorsAcetylcholine-induced currentsNicotinic acetylcholine responsesNicotinic currentsAcetylcholine responseNicotinic responsesComplete blockadeNicotinic receptorsSuperfusion methodPressure ejectionToxin applicationBlockadePatch electrodeBungarotoxinCellsHigh affinityResponseReceptors
1988
Spontaneous release of acetylcholine affects the physiological nicotinic responses of rat retinal ganglion cells in culture
Lipton S. Spontaneous release of acetylcholine affects the physiological nicotinic responses of rat retinal ganglion cells in culture. Journal Of Neuroscience 1988, 8: 3857-3868. PMID: 2903915, PMCID: PMC6569610, DOI: 10.1523/jneurosci.08-10-03857.1988.Peer-Reviewed Original ResearchConceptsRetinal ganglion cellsGanglion cellsEndogenous AChRetinal culturesMammalian retinal ganglion cellsOutward currentsRat retinal ganglion cellsCentral mammalian neuronsCholinergic amacrine cellsWhole-cell recordingsConcentrations of AChTonic currentsNicotinic currentsExogenous AChCholinergic responsesNicotinic antagonistsNicotinic responsesAmacrine cellsCentral neuronsNicotinic agonistsD-turbocurarineRetinal cellsTrophic effectsSpontaneous releaseIntact retina
1987
Neural nicotinic acetylcholine responses in solitary mammalian retinal ganglion cells
Lipton S, Aizenman E, Loring R. Neural nicotinic acetylcholine responses in solitary mammalian retinal ganglion cells. Pflügers Archiv - European Journal Of Physiology 1987, 410: 37-43. PMID: 3684508, DOI: 10.1007/bf00581893.Peer-Reviewed Original ResearchConceptsRetinal ganglion cellsGanglion cellsWhole-cell recordingsAcetylcholine responseNicotinic responsesNervous systemMammalian retinal ganglion cellsRat retinal ganglion cellsNicotinic channelsAutonomic ganglion cellsDihydro-β-erythroidineNicotinic receptor antagonistAcetylcholine-induced currentsPeripheral nervous systemNicotinic acetylcholine responsesAgonist-induced currentsCentral nervous systemPatch-clamp techniqueCholinergic responsesReceptor antagonistCentral neuronsToxin FD-tubocurarineNicotinic natureΑ-bungarotoxin