1985
Conditioning hyperpolarization reveals a property of the light-sensitive current in photoreceptors that is modified by cGMP and EGTA
Lipton S. Conditioning hyperpolarization reveals a property of the light-sensitive current in photoreceptors that is modified by cGMP and EGTA. Brain Research 1985, 341: 337-349. PMID: 2994819, DOI: 10.1016/0006-8993(85)91073-x.Peer-Reviewed Original Research
1983
cGMP and EGTA increase the light-sensitive current of retinal rods
Lipton S. cGMP and EGTA increase the light-sensitive current of retinal rods. Brain Research 1983, 265: 41-48. PMID: 6303507, DOI: 10.1016/0006-8993(83)91331-8.Peer-Reviewed Original ResearchMeSH KeywordsAmbystomaAnimalsCalciumCyclic GMPEgtazic AcidElectrophysiologyEthylene GlycolsIn Vitro TechniquesLightPhotoreceptor CellsVision, Ocular
1979
Ca2+ and photoreceptor adaptation
LIPTON S, OSTROY S, DOWLING J. Ca2+ and photoreceptor adaptation. Nature 1979, 281: 407-408. PMID: 481607, DOI: 10.1038/281407c0.Peer-Reviewed Original Research
1977
Electrical and adaptive properties of rod photoreceptors in Bufo marinus. II. Effects of cyclic nucleotides and prostaglandins.
Lipton S, Rasmussen H, Dowling J. Electrical and adaptive properties of rod photoreceptors in Bufo marinus. II. Effects of cyclic nucleotides and prostaglandins. The Journal Of General Physiology 1977, 70: 771-791. PMID: 201724, PMCID: PMC2228513, DOI: 10.1085/jgp.70.6.771.Peer-Reviewed Original ResearchConceptsCombination of drugsIsolated toad retinaCyclic nucleotide levelsCombination of IBMXResponse amplitudeDrug levelsReceptor sensitivityLong-term exposureReceptor saturationIntracellular cGMPMM IBMXRetinaControl RingerSimilar alterationsElectrical activityCGMPRod photoreceptorsV-log IATPase pumpRod activitySuperfusionDark adaptationOuter segmentsSensitivity recoveryCyclic nucleotidesElectrical and adaptive properties of rod photoreceptors in Bufo marinus. I. Effects of altered extracellular Ca2+ levels.
Lipton S, Ostroy S, Dowling J. Electrical and adaptive properties of rod photoreceptors in Bufo marinus. I. Effects of altered extracellular Ca2+ levels. The Journal Of General Physiology 1977, 70: 747-770. PMID: 412914, PMCID: PMC2228514, DOI: 10.1085/jgp.70.6.747.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, OcularAnimalsBufo marinusCalciumEvoked PotentialsIn Vitro TechniquesPhotic StimulationPhotoreceptor CellsTime FactorsConceptsReceptor sensitivityLight-evoked responsesResponse amplitudeLow calcium RingerMembrane potential levelMembrane potentialExtracellular Ca2Intracellular storesAdapted rodRod sensitivityReceptor potentialElectrical activityRod photoreceptorsRinger's solutionV-log IRingerDark adaptationProlonged exposureSensitivity recoveryRetinaResponse saturationSubstantial depolarizationBufo marinus