1997
Techniques for Distinguishing Apoptosis from Necrosis in Cerebrocortical and Cerebellar Neurons
Bonfoco E, Ankarcrona M, Krainc D, Nicotera P, Lipton S. Techniques for Distinguishing Apoptosis from Necrosis in Cerebrocortical and Cerebellar Neurons. Neuromethods 1997, 29: 237-253. DOI: 10.1385/0-89603-451-8:237.Peer-Reviewed Original ResearchCell deathCell typesRegulated cell deathDifferent cell typesSame cell typeApoptotic stimuliMorphological criteriaChromatin condensationChromatin degradationCleavage of DNADetection of apoptosisCell shrinkageApoptosisApoptotic cellsImmature T lymphocytesCerebellar neuronsMorphological alterationsAPO1Light microscopyMorphological patternsDNAMorphological appearanceExponential growthDifferent morphological patternsT cells
1990
Neuronal injury due to HIV-1 envelope protein is blocked by anti-gp120 antibodies but not by anti-CD4 antibodies.
Kaiser P, Offermann J, Lipton S. Neuronal injury due to HIV-1 envelope protein is blocked by anti-gp120 antibodies but not by anti-CD4 antibodies. Neurology 1990, 40: 1757-61. PMID: 2234433, DOI: 10.1212/wnl.40.11.1757.Peer-Reviewed Original ResearchConceptsAnti-CD4 antibodiesNeuronal injuryHuman immunodeficiency virus type 1Retinal ganglion cell neuronsImmunodeficiency virus type 1Absence of superinfectionHIV-1 envelope proteinAnti-gp120 antibodiesGanglion cell neuronsRat T cellsForm of neurotoxicityVirus type 1Envelope proteinNeurologic manifestationsVisual lossImmunodeficiency syndromeCentral neuronsT cellsT lymphocytesHIV-1Protein gp120CD4 moleculeCell neuronsGp120Type 1