2021
Protein S-Nitrosylation in Neuronal Development
Nakamura T, Zhang X, Oh C, Lipton S. Protein S-Nitrosylation in Neuronal Development. 2021, 91-105. DOI: 10.1201/9781003204091-10.Peer-Reviewed Original ResearchPost-translational modificationsProtein S-nitrosylationS-nitrosylationReactive nitrogen speciesNeuronal developmentNeuronal differentiationTranscription factor MEF2Protein-protein interactionsIon channel activityProtein traffickingEnzymatic functionCysteine thiolsProtein conformationCellular mechanismsChannel activityNormal brain developmentNitrogen speciesSynaptic functionNitric oxide actsPathological processesBiological actionsProteinNeuronal survivalBiological systemsNeurogenesis
1989
Growth Factors for Neuronal Survival and Process Regeneration: Implications in the Mammalian Central Nervous System
Lipton S. Growth Factors for Neuronal Survival and Process Regeneration: Implications in the Mammalian Central Nervous System. JAMA Neurology 1989, 46: 1241-1248. PMID: 2573331, DOI: 10.1001/archneur.1989.00520470113038.Peer-Reviewed Original ResearchConceptsNeuronal survivalClinical neurologistsMammalian central nervous systemCentral nervous systemPossible therapeutic approachesPotential clinical implicationsImmunodeficiency syndromeAxonal regenerationNeuronal transplantationNeurologic disordersTherapeutic approachesModulatory agentsNervous systemAlzheimer's diseaseClinical implicationsMammalian brainNerve growthNeuronal processesGrowth factorNeurologistsNumber of substancesDiseaseNeuronsProcess regenerationSurvival